Summary TNF-alpha and LT-alpha are involved in the pathogenesis of established lymphoproliferative diseases. Both molecules bind to TNFRI and TNFRII. TNFRI is the major mediator of the TNF pro-apoptotic and proliferative effects and TNFRII might enhance these effects. TNF receptors I and II are normally present on hematopoetic cells. TNFR II is cha...

By Tatjana Jevtović-Stoimenov, Danica Marković, Milena Despotović, Dušica Pavlović, Gordana Kocić