Spermine Oxidation Products Induce Mitochondrial Alterations on Tumor CellsCytotoxic products of polyamines generatedin situby an enzyme-catalyzed reaction may be useful as a new avenue in combating cancer. This study demonstrates that multidrug resistant (MDR) cancer cells (colon adenocarcinoma and melanoma) are significantly more sensitive than t...

By Enzo Agostinelli