Polypharmacy and the risk of drug-drug interactions in patients with rheumatoid arthritis
Introduction/Aim. Polypharmacy can increase the risk of side effects and cause adverse drug interactions with a significant impact on the course of the basic disease. The aim of the study was to determine the frequency of polypharmacy and examine its impact on the risk of drug-drug interactions in patients with rheumatoid arthritis (RA). The resear...
By Nikola Krstić, Nikola Stefanović, Milan Petronijević, Ivana Damnjanović
Monte Carlo Method Based QSAR Modeling of Coumarin Derivates as Potent HIV‐1 Integrase Inhibitors and Molecular Docking Studies of Selected 4‐phenyl Hydroxycoumarins
Summary In search for new and promising coumarin compounds as HIV-1 integrase inhibitors, chemoinformatic methods like quantitative structure-activity relationships (QSAR) modeling and molecular docking have an important role since they can predict desired activity and propose molecule binding to enzyme. The aim of this study was building of QSAR m...
By Jovana Veselinović, Aleksandar Veselinović, Andrey Toropov, Alla Toropova, Ivana Damnjanović, Goran Nikolić