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Introduction. Systemic lupus erythematosus (SLE) represents a multisystemic disease characterized by antibody production, complement activation, and immune complexes deposition. Certain types of malignancies occur more often, and conversely, some of them occur less often in SLE patients. Mucosal melanoma of the anorectal region represents a rare fo...

By Aleksandar Popović, Ivan Petković, Andrija Rančić, Aleksandra Dimitrijević, Vesna Brzački, Stefan Stankov, Andrija Jović, Sonja Stojanović

Aim. The aim of the paper was to examine the impact of disease duration and administered therapy on the development of metabolic syndrome (MetS) in patients with systemic lupus erythematosus (SLE). Material and methods. This study involved 55 patients (50 females and 5 males) with the diagnosis and 49 healthy controls of similar age. MetS was defin...

By Jovana Cvetković, Sonja Stojanović, Ivan Tasić, Bojana Stamenković, Jovan Nedović, Sanja Stojanović

Nowadays, the appropriate control of rheumatoid arthritis (RA) involves the absence of clinical disease activity, delaying joint destruction as long as possible and adequate quality of life of the affected. With currently available therapeutic modalities, this therapeutic goal can be achieved in a large number of patients. The aim of this research ...

By Sonja Stojanović, Bojana Stamenković, Jovan Nedović, Ivana Aleksić, Jovana Cvetković

Pulmonary arterial hypertension (PAH), which occurs in about 15% of patients with systemic sclerosis (SSc), is a progressive vasculopathy and despite modern therapeutic options is still one of the leading causes of death in these patients. We presented a patient diagnosed with the overlap syndrome (systemic sclerosis and rheumatoid arthritis) with ...

By Ivana Aleksić, Sandra Šarić, Bojan Ilić, Sonja Stojanović, Marina Deljanin-Ilić

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By Ivana Aleksić, Sonja Stojanović, Ivan Tasić, Bojana Stamenković

Summary To examine whether the presence of the rare A allele of the TNF-Alpha-308 G/A gene polymorphism is associated with erosive arthritis and rapid radiological progression of the disease. The examined group included 131 patients with early RA. Using the PCR-RFLP method, the TNF-Alpha-308 G/A gene polymorphism was determined for all patients. In...

By Sonja Stojanović, Bojana Stamenković, Jovan Nedović, Tatjana Jevtović-Stoimenov, Dušica Pavlović

Summary The aim of the paper was to show the diagnostic and therapeutic approaches to a patient suffering from osteomalacia, as well as differential diagnosis with osteoporosis. Osteomalacia (OM) is a metabolic disease of bones which appears as a result of defective mineralization of newly formed bone matrix in adults. Diagnosis of diseas...

By Nela Živković, Sonja Stojanović