Introduction/Aim. Chronic apical periodontitis represents dynamic continuation of the presence of endodontic infection in the root canal system of the tooth, when the innate and acquired immune responses are activated and various cells and inflammatory mediators are recruited, which cause the consequent destruction of periapical tissues and the dev...

By Jelena Popović, Tatjana Cvetković, Tanja Džopalić, Aleksandar Mitić, Marija Nikolić, Radomir Barac, Nenad Stošić, Antonije Stanković

Introduction. Standard biomarkers for the diagnosis and follow-up of chronic kidney disease patients are appropriate neither in early diagnostics, adequate follow-up and progression assessment nor in complication development risk assessment. For that reason, a search for new, more suitable biomarkers continues. Various studies suggested microRNAs a...

By Vladana Stojiljković, Nikola Stefanović, Marija Vukelić-Nikolić, Branka Đorđević, Jelena Bašić, Gordana Kocić, Tatjana Cvetković

Oxidative stress, as one of the pathophysiological mechanisms involved in the reduction of myocardial contractility, stimulates the proliferation of cardiac fibroblasts and the activation of matrix metalloproteinases, which leads to extracellular matrix remodeling. Left ventricular hypertrophy (LVH) is a well-known independent risk factor for cardi...

By Sandra Šarić, Tatjana Cvetković, Dejan Petrović, Valentina Mitić, Sanja Stojanović, Vladana Stoiljković, Marina Deljanin-Ilić

Summary Host response to antigen stimulation in chronic inflammatory periapical lesions is mainly controlled by the balance between proinflammatory and anti-inflammatory cytokines. The aim of this study was to determine the concentration of TGF-β1 in the tissue homogenates of periapical lesions and to analyse its level in relation to the sympto...

By Jelena Popović, Tatjana Cvetković, Tanja Džopalić, Aleksandar Mitić, Marija Nikolić, Radomir Barac

Summary The presence of diabetes mellitus leads to a decrease in life quality in all domains. The aim of our study was to evaluate the quality of life (QOL) in diabetic patients and the factors affecting it in type 2 diabetic mellitus patients. We conducted a cross-sectional study that included 86 patients with type 2 diabetes mellitus, i...

By Ana Spasić, Radmila Veličković Radovanović, Aleksandra Catić Đorđević, Nikola Stefanović, Tatjana Cvetković

Summary The aim of this study was to investigate the exogenous agmatine influence on nitrosative and oxidative stress parameters in acute phase of multiple sclerosis (MS) experimental model, experimental autoimmune encephalomyelitis (EAE). EAE was induced by subcutaneous injection of myelin basic protein (50 μg per animal). Sprague-Dawley ...

By Ivana Stojanović, Srđan Ljubisavljević, Ivana Stevanović, Slavica Stojnev, Radmila Pavlović, Dušan Sokolović, Aleksandar Petrović, Dušica Pavlović, Tatjana Cvetković