Combating Staphylococcus aureus (S. aureus) infections using antibacterial drugs is actually an ongoing effort to overcome resistance mechanism of this microorganism. In this paper, we discussed (1) the mechanisms of resistance to some of the most commonly used antimicrobial agents in the treatment of S. aureus: methicillin, vancomicyn and quinolones. In addition, (2) efflux pump mechanisms involved in maintaining homeostasis in the presence of compounds that inhibit S. aureus growth and reproduction, as well as mechanisms of resistance to a number of antibiotics, have been reviewed.
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Thais Pereira Lopes, Cristina Rodrigues dos Santos Barbosa, Nair Silva Macêdo, Jackelyne Roberta Scherf, Maria Apoliana Costa dos Santos, Thiago Sampaio de Freitas, Jaime Ribeiro Filho, Henrique Douglas Melo Coutinho, Abolghasem Siyadatpanah, Polrat Wilairatana, Francisco Assis Bezerra da Cunha, Alysson Pontes Pinheiro
(2022)
Pharmacological activities of allylbenzene and allylanisole phenylpropanoids: Inhibition of antibiotic resistance targets and toxicity profile in a Drosophila melanogaster model
Journal of King Saud University - Science, 34(4)
10.1016/j.jksus.2022.101995The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.