Overview of the possibility of bone replacement for the purpose of pre-prosthetic preparation of the patient

Marko Igić; Milena Kostić; Ana Pejčić; Nikola Gligorijević; Marija Jovanović; Nenad Stošić

doi:10.5937/afmnai40-37511

Review article

Published: 01.12.2022.

<< Prev | Next >>

PDF

https://doi.org/10.5937/afmnai40-37511

Overview of the possibility of bone replacement for the purpose of pre-prosthetic preparation of the patient

Abstract

The loss of the jaw bone, especially in the area of the alveolar process, can significantly complicate the procedure of prosthetic rehabilitation of prosthetic patients. The reason for the loss of the jaw bones are physiological and pathological processes. Bone replacements are widely used in the reconstruction of bone defects. The optimal characteristics of these materials are biocompatibility, bioinertness, biofunctionality and a special canalicular and intercanalicular system. Alloplastic bone replacements are inorganic, synthetic, biocompatible and bioactive bone replacements with osteoinductive potential. Hydroxyapatite is a preparation based on calcium phosphate. It has high biocompatibility, low immunogenicity and good osteoconductive characteristics. Poor properties are poor mechanical resistance as well as a low degree of resorption. Therefore, the research of chemically modified hydroxyapatites containing different ions was started. Calcium ions can be replaced by various metal ions like cobalt, aluminum, nickel, manganese, chromium, copper in a liquid medium.

Keywords:

bone replacements,

hydroxyapatite,

biocompatibility,

metal ions

References

Wakamura M, Kandori K, Ishikawa T. Surface structure and composition of calcium hydroxyapatites substituted with Al(III), La(III) and Fe(III) ions. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2000;164(2–3):297–305.

Li Y, Ho J, Ooi CP. Antibacterial efficacy and cytotoxicity studies of copper (II) and titanium (IV) substituted hydroxyapatite nanoparticles. Materials Science and Engineering: C. 2010;30(8):1137–44.

de Lima IR, Alves GG, Soriano CA, Campaneli AP, Gasparoto TH, Schnaider Ramos E, et al. Understanding the impact of divalent cation substitution on hydroxyapatite: An in vitro multiparametric study on biocompatibility. Journal of Biomedical Materials Research Part A. 2011;98A(3):351–8.

Tran N, Webster TJ. Increased osteoblast functions in the presence of hydroxyapatite-coated iron oxide nanoparticles. Acta Biomaterialia. 2011;7(3):1298–306.

Suchanek W, Yashima M, Kakihana M, Yoshimura M. Hydroxyapatite/Hydroxyapatite‐Whisker Composites without Sintering Additives: Mechanical Properties and Microstructural Evolution. Journal of the American Ceramic Society. 1997;80(11):2805–13.