Introduction. The loss of the jaw bone, especially in the area of the alveolar process, can significantly complicate the procedure of prosthetic rehabilitation of prosthetic patients. The reason for the loss of the jaw bones are physiological and pathological processes. Materials. Bone replacements are widely used in the reconstruction of bone defects. The optimal characteristics of these materials are biocompatibility, bioinertness, biofunctionality and a special canalicular and intercanalicular system. Alloplastic bone replacements are inorganic, synthetic, biocompatible and bioactive bone replacements with osteoinductive potential. Hydroxyapatite is a preparation based on calcium phosphate. It has high biocompatibility, low immunogenicity and good osteoconductive characteristics. Poor properties are poor mechanical resistance as well as a low degree of resorption. Therefore, the research of chemically modified hydroxyapatites containing different ions was started. Conclusion. Calcium ions can be replaced by various metal ions like cobalt, aluminum, nickel, manganese, chromium, copper in a liquid medium.
References
1.
Wakamura M, Kandori K, Ishikawa T. Surface structure and composition of calcium hydroxyapatites substituted with Al(III), La(III) and Fe(III) ions. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2000;164(2–3):297–305.
2.
Li Y, Ho J, Ooi CP. Antibacterial efficacy and cytotoxicity studies of copper (II) and titanium (IV) substituted hydroxyapatite nanoparticles. Materials Science and Engineering: C. 2010;30(8):1137–44.
3.
de Lima IR, Alves GG, Soriano CA, Campaneli AP, Gasparoto TH, Schnaider Ramos E, et al. Understanding the impact of divalent cation substitution on hydroxyapatite: An in vitro multiparametric study on biocompatibility. Journal of Biomedical Materials Research Part A. 2011;98A(3):351–8.
4.
Tran N, Webster TJ. Increased osteoblast functions in the presence of hydroxyapatite-coated iron oxide nanoparticles. Acta Biomaterialia. 2011;7(3):1298–306.
5.
Suchanek W, Yashima M, Kakihana M, Yoshimura M. Hydroxyapatite/Hydroxyapatite‐Whisker Composites without Sintering Additives: Mechanical Properties and Microstructural Evolution. Journal of the American Ceramic Society. 1997;80(11):2805–13.
6.
Paluszkiewicz C, Ślósarczyk A, Pijocha D, Sitarz M, Bućko M, Zima A, et al. Synthesis, structural properties and thermal stability of Mn-doped hydroxyapatite. Journal of Molecular Structure. 2010;976(1–3):301–9.
7.
Bigi A, Bracci B, Cuisinier F, Elkaim R, Fini M, Mayer I, et al. Human osteoblast response to pulsed laser deposited calcium phosphate coatings. Biomaterials. 2005;26(15):2381–9.
8.
Li Y, Nam CT, Ooi CP. Iron(III) and manganese(II) substituted hydroxyapatite nanoparticles: Characterization and cytotoxicity analysis. Journal of Physics: Conference Series. 2009;187:012024.
9.
Medvecký Ľ, Štulajterová R, Parilák Ľ, Trpčevská J, Ďurišin J, Barinov SM. Influence of manganese on stability and particle growth of hydroxyapatite in simulated body fluid. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2006;281(1–3):221–9.
10.
Pabbruwe MB, Standard OC, Sorrell CC, Howlett CR. Bone formation within alumina tubes: effect of calcium, manganese, and chromium dopants. Biomaterials. 2004;25(20):4901–10.
11.
Armulik A, Svineng G, Wennerberg K, Fässler R, Johansson S. Expression of Integrin Subunit β1B in Integrin β1-Deficient GD25 Cells Does Not Interfere with αVβ3 Functions. Experimental Cell Research. 2000;254(1):55–63.
12.
Farmer M, Darby I. Ridge dimensional changes following single‐tooth extraction in the aesthetic zone. Clinical Oral Implants Research. 2014;25(2):272–7.
13.
Misono M, Hall WK. Oxidation-reduction properties of copper-and nickel-substituted hydroxyapatites. The Journal of Physical Chemistry. 1973;77(6):791–800.
14.
Verardi S, Lombardi T, Stacchi C. Clinical and Radiographic Evaluation of Nanohydroxyapatite Powder in Combination with Polylactic Acid/Polyglycolic Acid Copolymer as Bone Replacement Graft in the Surgical Treatment of Intrabony Periodontal Defects: A Retrospective Case Series Study. Materials. 13(2):269.
15.
Boanini E, Gazzano M, Bigi A. Ionic substitutions in calcium phosphates synthesized at low temperature. Acta Biomaterialia. 2010;6(6):1882–94.
16.
Cerovic R, Juretic M, Belušic Gobic M, Rogic M. The use of extraoral autologous bone graft in alveolar ridge augmentation. Med Flum. 2014;50(2):176–80.
17.
Cenzi R, Arduin L, Zollino I, Casadio C, Scarano A, Carinci F. Alveolar ridge augmentation with calvaria, iliac crest and mandibular autologous bone grafts: a retrospective study on 261 implants. international journal of stomatology & occlusion medicine. 2010;3(2):89–94.
18.
Mertens C, Decker C, Seeberger R, Hoffmann J, Sander A, Freier K. Early bone resorption after vertical bone augmentation – a comparison of calvarial and iliac grafts. Clinical Oral Implants Research. 2013;24(7):820–5.
19.
Moy PK. Clinical Experience with Osseous Site Development Using Autogenous Bone, Bone Graft Substitutes, and Membrane Barriers. Oral and Maxillofacial Surgery Clinics of North America. 2001;13(3):493–509.
20.
Majzoub J, Ravida A, Starch-Jensen T, Tattan M, Suárez-López del Amo F. The Influence of Different Grafting Materials on Alveolar Ridge Preservation: a Systematic Review. Journal of Oral and Maxillofacial Research. 10(3).
21.
Hansson S, Halldin A. Alveolar ridge resorption after tooth extraction: A consequence of a fundamental principle of bone physiology. Journal of Dental Biomechanics. 2012;3(0).
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