Mechanochemical Synthesis, In vivo Anti-malarial and Safety Evaluation of Amodiaquine-zinc Complex
Summary So far, some prospective metal-based anti-malarial drugs have been developed. The mechanochemical synthesis and characterization of Zn (II) complex with amodiaquine and its anti-malarial efficacy on Plasmodium berghei-infected mice and safety evaluation were described in this study. Solvent-free mechanochemical synthesis and characterizatio...
By Rotimi Olusanya Arise, Sunday-Nwaso Elizabeth, Samuel Tobi Farohunbi, Mikhail Olugbemiro Nafiu, Adedibu Clement Tella
Antidiabetic and Antioxidant Activities of Ethanolic Extract of Dried Flowers of Moringa oleifera in Streptozotocin-induced Diabetic Rats
Abstract This study was undertaken to determine the antidiabetic and antioxidant effects of oral administration of ethanolic extract of Moringa oleiferaflower on stretozotocin-induced diabetic rats at 100, 200, and 300 mg/kg b.w. Thirty (30) male experimental albino rats were grouped randomly into six groups: groups A, B, and F are the con...
By Rotimi Olusanya Arise, Oluwaseun Ruth Aburo, Samuel Tobi Farohunbi, Adenike Adebola Adewale