SummaryThe aim of this study was to investigate the prognostic significance of troponin I, C-reactive protein and risk factors for the occurrence of complications after myocardial infarction.Troponin I and C-reactive protein values were analyzed in 38% of patients with complications (postinfarction angina, ventricular fibrillation, heart failure and fatal outcome) and in 62% of patients without complications. Values wererecorded on admission and between the eighth and tenth day of hospitalization.It was found that a larger number of risk factors (p = 0.00), diabetes mellitus (p = 0.02) and smoking (p = 0.01) were significantly associated with the complications. It was shown that hypertension increases the risk of developing heart failure after acute myocardial infarction (p = 0.02). It resulted with statistically non-significant difference in the observed values of troponin I between the group of patients with complications and the group without them (p = 0.22, p = 0.327). There was a statistically significant difference in the observed values of C-reactive protein in the two groups of patients (p = 0.00, p = 0.01).It can be concluded that the values of troponin I had no prognostic significance in risk stratification, while the values of C-reactive protein, individual risk factors and a large numberof risk factors hadsignificance in risk stratification after myocardial infarction.
References
1.
Schaub N, Reichlin T, Meune C, Twerenbold R, Haaf P, Hochholzer W, et al. Markers of Plaque Instability in the Early Diagnosis and Risk Stratification of Acute Myocardial Infarction. Clinical Chemistry. 2012;58(1):246–56.
2.
Keskin O, Ulusoy R, Kalemoglu M, Us M, Yildirim I, Tarcin O, et al. White Blood Cell Count and C-reactive Protein Predict Short-term Prognosis in Acute Myocardial Infarction. Journal of International Medical Research. 2004;32(6):646–54.
3.
Kuch B, von Scheidt W, Kling B, Heier M, Hoermann A, Meisinger C. Differential Impact of Admission C-Reactive Protein Levels on 28-Day Mortality Risk in Patients With ST-Elevation Versus Non–ST-Elevation Myocardial Infarction (from the Monitoring Trends and Determinants on Cardiovascular Diseases [MONICA]/Cooperative Health Research in the Region of Augsburg [KORA] Augsburg Myocardial Infarction Registry). The American Journal of Cardiology. 2008;102(9):1125–30.
4.
Nesto RW, Zarich S. Acute Myocardial Infarction in Diabetes Mellitus. Circulation. 1998;97(1):12–5.
5.
Bursi F, Weston SA, Killian JM, Gabriel SE, Jacobsen SJ, Roger VL. C-Reactive Protein and Heart Failure after Myocardial Infarction in the Community. The American Journal of Medicine. 2007;120(7):616–22.
6.
Suleiman M, Aronson D, Reisner SA, Kapeliovich MR, Markiewicz W, Levy Y, et al. Admission C-reactive protein levels and 30-day mortality in patients with acute myocardial infarction. The American Journal of Medicine. 2003;115(9):695–701.
7.
Morrow DA, Rifai N, Antman EM, Weiner DL, McCabe CH, Cannon CP, et al. C-Reactive Protein Is a Potent Predictor of Mortality Independently of and in Combination With Troponin T in Acute Coronary Syndromes: A TIMI 11A Substudy. Journal of the American College of Cardiology. 1998;31(7):1460–5.
8.
Gerber Y, Rosen LJ, Goldbourt U, Benyamini Y, Drory Y. Smoking Status and Long-Term Survival After First Acute Myocardial Infarction. Journal of the American College of Cardiology. 2009;54(25):2382–7.
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