This is an open uncontrolled study about the positive effects of a four-week rehabilitation spa program on the quality of life of 74 patients with ankylosing spondylitis. We assessed the following health status parameters on admission and discharge from the Institute Igalo, Montenegro: BASFI, BASDAI, ASDAS-CRP, ASAS 20 improvement criteria and SF-36 questionnaire. It was a "test-retest study". All the patients had six days of spa physical therapy per week during the four-week rehabilitation program, which made 24 therapy days in total. Therapy sets included the exercise program in gym and pool with mineral water, breathing exercises, massage therapy, balneotherapy (mud packs of baths, mineral and pearl baths, underwater massages), electrotherapy, sonotherapy, as well as thalassotherapy. Physiotherapy was prescribed by physician individually according to general health status and eventual contraindications. In all the observed parameters, statistical analysis showed that there was a highly significant improvement (p < 0.01). After four weeks of spa rehabilitation, ASAS 20 improvement index was achieved in 74.3% of patients with ankylosing spondylitis. Conclusions were that four weeks of complex spa physical therapy program in Institute Igalo led to a significant improvement of assessed parameters of disease activity, functional status and in domains of quality of life.
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