×
Home Current Archive Editorial board
News Contact
Research paper

Comparison of cognitive status of diabetic and non-diabetic elderly in the last ten years in primary health care in Iran

By
Vahidreza Borhaninejad ,
Vahidreza Borhaninejad
Maryam Saber
Maryam Saber

Abstract

Introduction. Cognitive disorders and chronic diseases such as diabetes are common problems of aging. The aim of this study was to determine and compare the cognitive status of diabetic and non-diabetic elderly in the past ten years in primary health care in Iran. Method: This cross-sectional study was performed on people aged 60 years and older in Kerman, Iran in 2020. In total, this study was performed on 200 patients (100 diabetic and 100 non-diabetic) meeting inclusion criteria. The Short Mental Status Questionnaire (MMSE) and The Informant Questionnaire for Cognitive Decline in the Elderly (IQCODE) were used to assess cognitive function. The validity and reliability of the questionnaires were confirmed in this study. Data were analyzed using Chi-square, T-test, and ANOVA analysis in SPSS 21 software. Results. The results showed that there was a statistically significant difference between diabetic and non-diabetic groups in the current cognitive status and cognitive status in the last ten years. The mean scores of cognitive function from the short mental status questionnaire in the diabetic group were lower than in the non-diabetic group (p = 0.001). The mean scores of the cognitive deficit screening questionnaire in diabetic elderly were higher than in non-diabetic elderly (p < 0.001). Conclusion. Based on the results of this study, health care providers and family physicians should focus on controlling diabetes and identifying any cognitive impairment in the early stages of comprehensive care of diabetic patients.

References

1.
Rashid AK, Azizah AM, Rohana S. Cognitive impairment among the elderly Malays living in rural Malaysia. Med J Malaysia. 2012;9.
2.
Haroon NN, Austin PC, Shah BR, Wu J, Gill SS, Booth GL. Risk of Dementia in Seniors With Newly Diagnosed Diabetes: A Population-Based Study. Diabetes Care. 2015;38(10):1868–75.
3.
Li J, Cesari M, Liu F, Dong B, Vellas B. Effects of Diabetes Mellitus on Cognitive Decline in Patients with Alzheimer Disease: A Systematic Review. Canadian Journal of Diabetes. 2017;41(1):114–9.
4.
Teixeira MM, Passos VMA, Barreto SM, Schmidt MI, Duncan BB, Beleigoli AMR, et al. Association between diabetes and cognitive function at baseline in the Brazilian Longitudinal Study of Adult Health (ELSA- Brasil). Scientific Reports. 10(1).
5.
Roberts RO, Knopman DS, Przybelski SA, Mielke MM, Kantarci K, Preboske GM, et al. Association of type 2 diabetes with brain atrophy and cognitive impairment. Neurology. 2014;82(13):1132–41.
6.
Macpherson H, Formica M, Harris E, Daly RM. Brain functional alterations in Type 2 Diabetes – A systematic review of fMRI studies. Frontiers in Neuroendocrinology. 2017;47:34–46.
7.
Malekian N, Hosseini SR, Moudi S, Bayani MA, Kheirkhah F, Bijani A, et al. Type 2 Diabetes Mellitus and Cognitive Function in the Elderly. Iranian Journal of Psychiatry and Behavioral Sciences. 12(2).
8.
Hatami H, Eshrati B, Kalateh E. Health Survey of Elderly Residents in Rural Areas of Ashtian City: Markazi Province, 2015. Salmand. 11(2):250–7.
9.
Golmakani N, Shaghaghi F, Ahmadi Z, Gholami M, Kamali Z, Mohebbi-Dehnavi Z. Investigating the relationship between the dimensions of mindfulness and maternal attachment to the fetus during pregnancy. Journal of Education and Health Promotion. 10(1).
10.
Paknahad Z, Tarrahi M, Shaghaghi F. The role of micronutrients in male and female fertility: A review study. IJOGI. 2021;24(1):87–98.
11.
Spauwen PJJ, Köhler S, Verhey FRJ, Stehouwer CDA, van Boxtel MPJ. Effects of Type 2 Diabetes on 12-Year Cognitive Change. Diabetes Care. 2013;36(6):1554–61.
12.
Gudala K, Bansal D, Schifano F, Bhansali A. Diabetes mellitus and risk of dementia: A meta‐analysis of prospective observational studies. Journal of Diabetes Investigation. 2013;4(6):640–50.
13.
Paúl C, Ribeiro O, Santos P. Cognitive impairment in old people living in the community. Archives of Gerontology and Geriatrics. 2010;51(2):121–4.
14.
Sharp ES, Gatz M. Relationship Between Education and Dementia. Alzheimer Disease &amp; Associated Disorders. 2011;25(4):289–304.
15.
Wu MS, Lan TH, Chen CM, Chiu HC, Lan TY. Socio-demographic and health-related factors associated with cognitive impairment in the elderly in Taiwan. BMC Public Health. 2011;11(1).
16.
Rodríguez-Sánchez E, Mora-Simón S, Patino-Alonso MC, García-García R, Escribano-Hernández A, García-Ortiz L, et al. Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study. BMC Neurology. 2011;11(1).
17.
Hatami H. Healthy Ageing in Iranian Traditional Medicine’s Resources in the Occasion of the World Health Day 2012.
18.
Peters ME, Rosenberg PB, Steinberg M, Tschanz JT, Norton MC, Welsh-Bohmer KA, et al. Prevalence of Neuropsychiatric Symptoms in CIND and Its Subtypes: The Cache County Study. The American Journal of Geriatric Psychiatry. 2012;20(5):416–24.
19.
Valizadeh R, Vali L, Bahaadinbeigy K, Amiresmaili M. The Challenges of Iran’s Type 2 Diabetes Prevention and Control Program. International Journal of Preventive Medicine. 2019;10(1).
20.
Soleimani Tapehsari B, Alizadeh M, Khamseh ME, Seifouri S, Nojomi M. Physical Activity and Quality of Life in People with Type 2 Diabetes Mellitus: A Randomized Controlled Trial. International Journal of Preventive Medicine. 2020;11(1).
21.
R. S, M. T, M GR. Kangaroo mother care for infantile colic: a randomized clinical trial. Tehran Univ Med J. 2010;67(12):870–5.
22.
S. P, R. KH, M. GR, Z. G, R S. Evaluation of massage with oil containing medium chain triglyceride on weight gaining in preterm. Koomesh. 2009;11(1):1–6.
23.
Li W, Sun L, Xiao S. Prevalence, Incidence, Influence Factors, and Cognitive Characteristics of Amnestic Mild Cognitive Impairment Among Older Adult: A 1-Year Follow-Up Study in China. Frontiers in Psychiatry. 11.
24.
Li Q, Guo J, Cao X, Yuan X, Rao K, Zheng Z, et al. Trend of non‐communicable disease mortality for three common conditions in the elderly population from 2002 to 2010: A population‐based study in China. Chronic Diseases and Translational Medicine. 2015;1(3):152–7.
25.
Mohseni M, Iranpour A, Naghibzadeh-Tahami A, Kazazi L, Borhaninejad V. The relationship between meaning in life and resilience in older adults: a cross-sectional study. Health Psychology Report. 2019;7(2):133–8.
26.
Borhaninejad V, Shati M, Bhalla D, Iranpour A, Fadayevatan R. A Population-Based Survey to Determine Association of Perceived Social Support and Self-Efficacy With Self-Care Among Elderly With Diabetes Mellitus (Kerman City, Iran). The International Journal of Aging and Human Development. 2017;85(4):504–17.
27.
Khodabakhshi H, Tiyuri A, Yari E, Beheshti D, Sharifzadeh G. Prevalence of Non-Communicable Disease Risk Factors Among the Elderly of Birjand in 2014. Iran J Ageing. 2019;14:52–63.
28.
Thompson G, Foth D. Cognitive-Training Programs for Older Adults: What Are they and Can they Enhance Mental Fitness? Educational Gerontology. 2005;31(8):603–26.
29.
Ray S, Dementia DS, decline. A review of the evidence Age UK. 2014;27:10–2.
30.
Murman D. The Impact of Age on Cognition. Seminars in Hearing. 36(03):111–21.
31.
Nejati V. Cognitive-executive functions of brain frontal lobe in aged adults. International JBS. 2010;4:59–64.
32.
Langa KM, Larson EB, Crimmins EM, Faul JD, Levine DA, Kabeto MU, et al. A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012. JAMA Internal Medicine. 2017;177(1):51.
33.
Aajami Z, kazazi L, Troski M, Bahrami M, Borhaninejad V. Relationship between Depression and Cognitive Impairment among Elderly: A Cross-sectional Study. Journal of Caring Sciences. 9(3):148–53.
34.
Goeppel C, Frenz P, Tinnemann P, Grabenhenrich L. Universal health coverage for elderly people with non-communicable diseases in low-income and middle-income countries: a cross-sectional analysis. The Lancet. 2014;384:S6.
35.
Ren L, Bai L, Wu Y, Ni J, Shi M, Lu H, et al. Prevalence of and Risk Factors for Cognitive Impairment Among Elderly Without Cardio- and Cerebrovascular Diseases: A Population-Based Study in Rural China. Frontiers in Aging Neuroscience. 10.
36.
Plastino M, Fava A, Pirritano D, Cotronei P, Sacco N, Sperlì T, et al. Effects of insulinic therapy on cognitive impairment in patients with Alzheimer disease and Diabetes Mellitus type-2. Journal of the Neurological Sciences. 2010;288(1–2):112–6.
37.
Xu W, Qiu C, Gatz M, Pedersen NL, Johansson B, Fratiglioni L. Mid- and Late-Life Diabetes in Relation to the Risk of Dementia. Diabetes. 2009;58(1):71–7.
38.
Baker LD, Cross DJ, Minoshima S, Belongia D, Watson GS, Craft S. Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes. Archives of Neurology. 2011;68(1).
39.
van Gemert T, Wölwer W, Weber KS, Hoyer A, Strassburger K, Bohnau NT, et al. Cognitive Function Is Impaired in Patients with Recently Diagnosed Type 2 Diabetes, but Not Type 1 Diabetes. Journal of Diabetes Research. 2018;2018:1–10.
40.
Woodford HJ, George J. Cognitive assessment in the elderly: a review of clinical methods. QJM. 100(8):469–84.
41.
Foroughan M, Jafari Z, Bayan PS, Faraahani ZGM, Rahgozar M. Validation of mini-mental state examination (mmse) in the elderly population of tehran. Adv CognSci. 2008;10:29–37.
42.
Phung TKT, Chaaya M, Asmar K, Atweh S, Ghusn H, Khoury RM, et al. Performance of the 16-Item Informant Questionnaire on Cognitive Decline for the Elderly (IQCODE) in an Arabic-Speaking Older Population. Dementia and Geriatric Cognitive Disorders. 2015;40(5–6):276–89.
43.
Foroughan M, Jafari Z, Ghaemmagham Farahani I, Rashedi V. Validity and Reliability of the Informant Questionnaire on Cognitive      Decline in the Elderly (IQCODE). GeroPsych. 2019;32(3):145–51.
44.
van den Berg E, Reijmer YD, de Bresser J, Kessels RPC, Kappelle LJ, et al. A 4 year follow-up study of cognitive functioning in patients with type 2 diabetes mellitus. Diabetologia. 2010;53(1):58–65.

Citation

Article metrics

Google scholar: See link

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.