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Vol 39, No 4 (2022)

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Authors in this issue:

Adisa Hasković-Džubur, Aksanur Gokce, Alem Čolaković, Amina Selimović, Andrii Formanchuk, Andrija Jović, Andrija Šmelcerović, Anelia Mavrova, Arsovska Mirceska, Belma Memić, Danica Tiodorović, Dejan Dobrijević, Denis Hasković, Denitsa Yancheva, Dinakar Jayakumar, Dušica Stojanović, Edhem Hasković, Elma Avdagić-Golub, Gowri Shanmugasundaram, Gül Akın, Harun Uzunalıć, Hryhoriy Lapshyn, Igor Vovchuk, Işılay Taşkaldıran, Ivana Ilić-Savić, Jasmina Katanić, Jelena Lazarević, Jelena Zvezdanović, Jovanka Kolarović, Katerina Damevska, Konstansa Lazarević, Ljiljana Stošić, Marija Tasić-Kostov, Mariya Pokidko, Mehmet Koksal, Mirjana Petrović-Lazić, Muhamed Begović, Mustafa Çelikc, Mustafa Doğan, Nataša Kaćanski-Rađenović, Neda Anastassova, Onur Esbah, Recep Eröz, Safija Herenda, Sanja Stanković, Snežana Babac, Snežana Unčanin, Tetiana Formanchuk, Tulay Omma, Varshini Marimuthu, Viktor Simeonovski,

Published: 01.01.2022.

Contents

01.12.2021. Research paper
Application of machine learning in the fight against the COVID-19 pandemic: A review

Introduction: Machine learning (ML) plays a significant role in the fight against the COVID-19 (officially known as SARS-CoV-2) pandemic. ML techniques enable the rapid detection of patterns and trends in large datasets. Therefore, ML provides efficient methods to generate knowledge from structured and unstructured data. This potential is particula...

By ALEM ČOLAKOVIĆ, ELMA AVDAGIĆ-GOLUB, MUHAMED BEGOVIĆ, BELMA MEMIĆ, ADISA HASKOVIĆ-DŽUBUR

01.12.2021. Research paper
Formulation of biologics for alternative routes of administration: Current problems and perspectives

Introduction: Biologics (biopharmaceuticals) present new promising therapies for many diseases such as cancers, chronical inflammatory diseases and today's biggest challenge - COVID-19. Research: Today, most biologics have been synthetized using modern methods of biotechnology, in particular DNA recombinant technology. Current pharmaceutical forms ...

By SANJA STANKOVIĆ, MARIJA TASIĆ-KOSTOV

01.12.2021. Research paper
The impact of the COVID-19 pandemic on the quality of life of laryngectomized patients

Introduction: Quality of life is a state of complete physical, mental and social well-being. Due to the COVID-19 pandemic, which led to changes in the daily routine, there was a change in the psychosocial functioning of individuals. Given that laryngectomized patients belong to a vulnerable group that requires psychological support after surgery, s...

By MIRJANA PETROVIĆ-LAZIĆ, SNEŽANA BABAC, IVANA ILIĆ-SAVIĆ

01.12.2021. Research paper
Could nucleolin and nucleophosmin levels be prognostic indicators in non-small cell lung cancer?

Aim: Lung cancer is the leading cause of mortality from cancer across the world. In this study, the use of serum nucleolin (NCL) and nucleophosmin (NPM1) levels as a marker in the diagnosis, prognosis and treatment response evaluation in lung cancer was investigated. Materials and Method: NCL and NPM1 levels of serum samples taken before chemothera...

By GÜL AKIN, ONUR ESBAH, RECEP ERÖZ

01.12.2021. Research paper
In vitro assessment of the lipid peroxidation of N,N'-disubstituted benzimidazole-2-thiones: Hydrazides vs esters

Introduction: Oxidative stress and resulting lipid peroxidation are involved in numerous pathological conditions. For this reason, the role of antioxidants attracts attention and the radical-scavenging capacity of many natural and synthetic supplements and drugs has been extensively evaluated. Material and methods: In the present study, seven N,N'-...

By JELENA LAZAREVIĆ, JELENA ZVEZDANOVIĆ, NEDA ANASTASSOVA, ANELIA MAVROVA, DENITSA YANCHEVA, ANDRIJA ŠMELCEROVIĆ

01.12.2021. Research paper
The relationship between neutrophil-lymphocyte ratio and clinal laboratory data in acute pancreatitis

Introduction: Neutrophil-lymphocyte ratio (NLR) is one of the laboratory biomarkers used in clinical practice to predict severity and mortality of acute pancreatitis (AP), however, there is currently insufficient information about the changes of NLR in the dynamics in relationship with other clinical and laboratory data. Aims: To assess the relatio...

By TETIANA FORMANCHUK, HRYHORIY LAPSHYN, MARIYA POKIDKO, ANDRII FORMANCHUK, IGOR VOVCHUK

01.12.2021. Research paper
An analysis of laboratory parameters of chronic kidney failure in elderly patients

Aim: The chief aim of this study was monitoring of laboratory parameters of chronic kidney failure in elderly patients. Methods: All samples were taken and processed by standard methods and according to the principles of good laboratory practice. Data were collected in an organized and systematic manner in the form of a questionnaire with respect t...

By EDHEM HASKOVIĆ, HARUN UZUNALIĆ, SNEŽANA UNČANIN, SAFIJA HERENDA, DENIS HASKOVIĆ, AMINA SELIMOVIĆ

01.12.2021. Research paper
An overview of the hematological picture with antithyroid therapy in Graves' disease

Aim: Graves' disease is an autoimmune thyroid disease that is the most common cause of hyperthyroidism. Peripheral blood cell parameters such as neutrophils, lymphocytes, and platelets play a role in inflammation control. Several studies have proven that neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio and platelet-lymphocyte ratio are indica...

By AKSANUR GOKCE, TULAY OMMA, MUSTAFA ÇELIKC, IŞILAY TAŞKALDIRAN

01.12.2021. Research paper
Neurological and psychiatric comorbidities in bullous pemphigoid

Introduction: Bullous pemphigoid (BP) is an autoimmune skin disease that typically presents with severe itching and blistering, with or without eczematous and urticarial lesions. Patients with BP are at an increased risk of comorbid conditions, especially neurologic and psychiatric diseases. Several recent studies have found a link between BP and n...

By ARSOVSKA MIRCESKA, KATERINA DAMEVSKA, VIKTOR SIMEONOVSKI, ANDRIJA JOVIĆ, DANICA TIODOROVIĆ

01.12.2021. Research paper
The relationship between community noise and arterial hypertension in the population of the city of Niš

Aim: The aim of the study was to examine the relationship between noise exposure and the incidence of arterial hypertension as well as the relationship of noise annoyance and noise sensitivity with hypertension. Methods: A cross-sectional questionnaire survey was performed on 911 adult residents of Niš, Serbia, of whom 388 were men (42.6%) and 523 ...

By LJILJANA STOŠIĆ, DUŠICA STOJANOVIĆ, KONSTANSA LAZAREVIĆ

01.12.2021. Research paper
Pseudothrombocytopenia induced by ethylenediaminetetraacetic acid: A case report

Introduction: Pseudothrombocytopenia induced by ethylenediaminetetraacetic acid is a rare phenomenon caused by autoantibodies against platelet membrane with overall prevalence of 0.1% in the general population. This phenomenon is an in vitro artifact and with different anticoagulant used, the patient had the physiological platelet count. Case repor...

By DEJAN DOBRIJEVIĆ, NATAŠA KAĆANSKI-RAĐENOVIĆ, JASMINA KATANIĆ, JOVANKA KOLAROVIĆ

01.12.2021. Research paper
Heterozygous c.1730G > C (p.Trp577Ser) variation in a case with familial hypercholesterolemia

Introduction: FH is an autosomal dominant disease of lipid metabolism. Hypercholesterolemia, xanthomas, and death from early coronary artery disease (CAD) are common in this disease due to a mutation in the LDLR, Apo-B100 or PCSK9 genes. Case report: A 4-year-old male patient with a very rare heterozygous c.1730G > C (p.Trp577Ser) variation in e...

By MUSTAFA DOĞAN, MEHMET KOKSAL, RECEP EROZ

01.12.2021. Research paper
Clinical and cytopathological traits of herpes zoster: A report of two cases

Introduction: Varicella zoster virus is a highly infectious a-herpesvirus, pathogenic only to humans. The primary infection of varicella zoster virus causes chickenpox, which is contagious and primarily infects children and adolescents in India. Following the primary infection, the virus remains dormant in sensory root ganglia. Activation of the do...

By VARSHINI MARIMUTHU, DINAKAR JAYAKUMAR, GOWRI SHANMUGASUNDARAM

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