Skin challenges in COVID-19 pandemic: The importance of cosmeceuticals
Introduction. Although COVID-19 is present in a milder form nowadays, systemic disorders caused by the virus lead to multiple organ malfunctions. Skin manifestations are the consequence of the disease itself but also the result of preventative measures taken to avoid the infection. They generally do not require pharmacotherapy except in severe case...
By Marija Tasić-Kostov
In vitro antimicrobial activity of different Verbascum niveum extracts
Introduction. Medicinal plants are the main ingredient of numerous medicines and pharmaceutical products, and antimicrobial activity has been demonstrated in a large number of medicinal plant extracts and essential oils. Considering that Verbascum L. species (mullein), officially approved by the European Medicines Agency, show antimicrobial propert...
By Maja Grigorov, Dragana Pavlović, Snežana Mladenović-Antić, Marija Tasić-Kostov, Dušan Ilić
Formulation of biologics for alternative routes of administration: Current problems and perspectives
Introduction: Biologics (biopharmaceuticals) present new promising therapies for many diseases such as cancers, chronical inflammatory diseases and today's biggest challenge - COVID-19. Research: Today, most biologics have been synthetized using modern methods of biotechnology, in particular DNA recombinant technology. Current pharmaceutical forms ...
By Sanja Stanković, Marija Tasić-Kostov
Spectrophotometric method in comparative in vitro dissolution test of branded and generic ibuprofen tablets
The dissolution test is a simple and important in vitro method for assessing the bioequivalence, which aims to compare the bioavailability of generic and branded drugs. It implies the use of a proper apparatus (usually pharmacopoeially defined) in which the dosage form is dissolved, and the dissolution process itself is monitored/quantified using a...
By Ana Marković, Miroslava Spasić, Vesna Savić, Slavica Sunarić, Marija Tasić-Kostov
Alkyl polyglucoside-based emulsions as vehicles for topical spironolactone: A textural analysis
Acne vulgaris is a chronic dermatological disease that affects the pilosebaceous unit; androgens play an important role in its pathogenesis. Acne therapy can be either systemic or topical, usual in the treatment of mild and moderate forms of acne. Spironolactone (SP) is an anti-androgen drug with potential to reduce the sebum secretion; in order to...
By Dušan Ilić, Maja Cvetković, Marija Tasić-Kostov
Off-label prescriptions in dermatology: Challenges of new routes of administration for certain old drugs
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By Marija Tasić-Kostov, Dušan Ilić