Epidermal growth factor receptor (EGFR) is one of the key tumor markers of non-small cell lung cancer (NSCLC) and a guideline for the choice of therapeutic procedures. The research aims to evaluate the methods used in the investigation of EGFR variants in NSCLC cell lines and combined research (NSCLC cell lines and patient samples) in the last deca...

By Jovana Todosijević-Jovanović, Jasmina Obradović, Vladimir Jurišić

Anemia is a common extraintestinal manifestation of inflammatory bowel diseases (IBDs). Recognizing and treating anemia in patients with IBD is vital for improving the quality of life and reducing complications. The aim of this study was to assess the effectiveness and safety of the liposomal iron formulation in the treatment of anemia in patients ...

By Srđan Marković, Đorđe Kralj, Tamara Knežević-Ivanovski, Miloš Mitrović, Olga Odanović, Vesna Brzački, Petar Svorcan

Depression is a mood disorder that prevents the patients from performing everyday activities, due to the constant presence of negative feelings. Depression is a worldwide medical disorder which is highly prevalent and has therefore become a huge financial burden for the health system. Biological, psychological, and social factors are most commonly ...

By Ina Konstantinović, Milena Trandafilović

Introduction. Since 1999 continuous glucose monitoring (CGM) has been used to measure the amount of glucose in the interstitial fluid. CGM is crucial when it comes to developing the ambulatory glucose profile and giving information on time spent in range (TIR), percentage of time spent above and below range, as well as variability. Discussion. It w...

By Milovan Stojanović, Milica Pešić, Stevan Ilić, Marina Deljanin-Ilić, Vojislav Ćirić

Introduction. Homocysteine is an amino acid that is formed in the metabolism of methionine as the quantitatively most important metabolite. Its chemical structure has been known for 90 years and its biological roles are still being investigated. Under normal conditions, homocysteine is present in plasma at the concentration of 5 - 9 mmol/l. When th...

By Bojana Miladinović, Vladana Živković, Dušanka Kitić, Maja Nikolić

Aims. The aim of the study was to assess the effectiveness of robotic-assisted gait treadmill training (Lokomat) as an adjunct to traditional physiotherapy in improving the range of motion, muscle strength and decreasing spasticity in lower extremities in children with cerebral palsy. Materials and Methods. Twenty-six participants, with mean 7.69 &...

By Dragana Đurić, Snežana Ilić, Alameri Shaima, Almenhali Ameera, Al Tariq

Introduction. Lemon balm has been used for centuries due to its strong sedative, antimicrobial and spasmolytic effects. Besides different types of extracts and essential oils, hydrolates (by-products obtained during essential oil extraction) are preparations of aromatic medicinal plants with potential pharmacological activity. Aim. To estimate Meli...

By Nikola Stojanović, Sara Mladenović, Bogdan Stojiljković, Aleksandar Marković, Dragana Pavlović, Pavle Ranđelović, Jelena Zvezdanović, Ljiljana Stanojević

Introduction. Sleep disturbance is a frequent complaint of patients suffering from arterial hypertension (AH) for a long time. A hidden and uncontrolled increase in blood pressure (BP) makes the course of physiological processes more difficult, disrupts the regulation of biological rhythms, and increases the risk of cardiovascular complications eve...

By Mikhail Osadchuk, Inna Vasilieva, Ekaterina Mironova, Nikolay Korzhenkov, Maxim Trushin

Introduction. Aesthetic appearance is one of the major concerns in adolescent idiopathic scoliosis (AIS) patients and its improvement is one of the main treatment's goals. Poor trunk appearance is associated with reduced quality of life in adolescents with idiopathic scoliosis. Aim. To review instruments that have been created to evaluate poor trun...

By Vesna Živković, Lidija Dimitrijević, Hristina Čolović, Dragan Zlatanović, Marija Spalević, Nataša Savić

Background and Aim: The aim of the present study was to compare the effect of volatile induction and maintenance of anesthesia (VIMA) and target controlled infusion (TCI) on cardiovascular stability in New York Heart Association (NYHA) grade II patients who underwent laparoscopic cholecystectomy. Patients and methods: In the present study, 90 patie...

By Biljana Stošić, Marija Stošić, Jelena Živadinović, Ines Veselinović