Introduction/Aim. Lentigo maligna (LM) represents an in situ melanoma that develops on chronically photo-damaged skin. Clinical diagnosis of LM is often difficult, even for experienced dermatologists. The aim of the study was to analyze the clinical and dermoscopic features of patients with pathohistologically verified lentigo maligna (LM) and to d...

By Danica Tiodorović, Danijela Popović, Slađana Cekić, Milica Radić, Aleksandar Popović, Nataša Vidović, Andrija Jović

Introduction. Cardiac metastasis of uterine cervical cancer diagnosed prior to mortality (antemortem) is extremely rare. Case report. A female patient 49 years old was brought to the Emergency Department of the Institute for Treatment and Rehabilitation Niška Banja in cardiac arrest, without a pulse and blood pressure. An electrocardiogram r...

By Milovan Stojanović, Bojan Ilić, Dragan Marinković, Sandra Šarić, Dejan Hristov, Marina Deljanin-Ilić

Introduction. The incidence of liver cancer is increasing globally. Fatty acids in lipid metabolism are associated with cancer risk by maintaining cancer cell membrane structure and transducing cancer signaling, and their increased synthesis promotes tumor growth, angiogenesis, and tumor metastasis. Methods. After identification of the ELOVL3 gene ...

By Yiyang Chen, Wanbang Zhou, Yiju Gon, Xi Ou

Introduction. Acrania is a very rare lethal congenital malformation characterized by an absence of the cranial vault with developed cerebral hemispheres. It is sometimes confused with anencephaly in which both the forebrain and neurocranium are not developed. Although these two conditions principally differ in their morphology and pathogenesis, acr...

By Vladimír Bartoš, Oľga Káčeríková

Introduction: This present study focuses on the findings of clinical trials that have revealed unsatisfactory results and mortality escalation rates of patients suffering from serious traumatic brain injuries (TBI). Aim: The main objective of this research was to investigate whether hyperglycaemia is a significant indicator of mortality in patients...

By Awatara Danta, Thirza Quila

Introduction. The loss of the jaw bone, especially in the area of the alveolar process, can significantly complicate the procedure of prosthetic rehabilitation of prosthetic patients. The reason for the loss of the jaw bones are physiological and pathological processes. Materials. Bone replacements are widely used in the reconstruction of bone defe...

By Marko Igić, Milena Kostić, Ana Pejčić, Nikola Gligorijević, Marija Jovanović, Nenad Stošić

Introduction. Hepatitis A virus is a major cause of acute viral hepatitis worldwide, with approximately 1.5 million cases annually. Clinical manifestations of the hepatitis A virus infection range from asymptomatic to acute liver failure. Cholestatic viral hepatitis A is a rare clinical manifestation characterized by a prolonged course, refractory ...

By Nemanja Đorđević, Predrag Čanović, Dejan Petrović, Nataša Minić, Željko Mijailović

Introduction/Aim. Roughly six percent of all malignancies diagnosed in children are malignant bone tumors. They have a dramatic effect on psychological status of children and their families. The aim of the study was to analyze the clinico-pathological features of bone tumors in Iraqi children and to assess response to treatment, outcome, and surviv...

By Abbas Olewi, Hayder Al-Zubaidi, Manaf Ahmed, Zaid Al-Attar

Introduction. Standard biomarkers for the diagnosis and follow-up of chronic kidney disease patients are appropriate neither in early diagnostics, adequate follow-up and progression assessment nor in complication development risk assessment. For that reason, a search for new, more suitable biomarkers continues. Various studies suggested microRNAs a...

By Vladana Stojiljković, Nikola Stefanović, Marija Vukelić-Nikolić, Branka Đorđević, Jelena Bašić, Gordana Kocić, Tatjana Cvetković

Background. Necrotizing soft tissue infections are actually the diseases with a severe outcome characterized by the progression of soft tissue inflammation with a catastrophic prognosis and the risk of major functional consequences. Only prompt diagnosis and prompt care, including prompt administration of appropriate antibiotic therapy and surgical...

By Mladen Kasalović, Gojko Igrutinović, Zlatan Elek, Aleksandar Jakovljević, Nikola Miljković, Milica Milentijević