This present research work was designed to investigate the potential chemopreventive effects of Annona Muricata on cadmium-induced hepatotoxicity and oxidative neuronal damage in Wistar albino rats. In this study, twenty-eight (28) Wistar albino rats were randomized into four groups, with seven rats each. Group A served as the control and provided ...

By Johnson Oladele, Omowumi Adewale, Olu Oyewole, Mistura Salami, Ganiyat Owoade, Oyedotun Oyeleke

The aim of our study was to investigate if green tea and bilberry have protective effect on gentamicin-induced kidney damage, when applied together, and to make a connection between their effects. GM group of rats received only gentamicin, GT group received green tea only, B group received only bilberry, whereas control (C) group received saline on...

By Milica Veljković, Dragana Pavlović, Ivan Ilić, Dušan Sokolović

Analysis of arterial blood gases is necessary for managing the respiratory and metabolic parameters of patients in the intensive care unit. The aim of this study was to compare the effects of heparin 1000 and heparin 5000 units on arterial blood gases in patients admitted to the intensive care unit. This study was a triple-blinded clinical trial. A...

By Reza Borabadi, Mostafa Rad, Mohammad Rakhshani, Mojtaba Rad

The waiting time for patients in the emergency department to receive health services influences many processes in this department. This research aimed to determine the effect of implementation and deployment of emergency severity index (ESI) on the waiting time for patients to receive health services in the emergency department. This quasi-experime...

By Akbar Sarvari, Hosein Habibzadeh, Leyla Alilu, Naser Sheikhi

Hyperuricemia and chronic deposition of monosodium urate crystals are the main cause of the gout. Urate lowering therapy (ULT) is the mainstay of chronic gout treatment. In this study, we evaluated demographic features and disease properties of the patients that would relate with the success of ULT. Sixty-six gout patients on pharmacologic ULT were...

By Nimet Kalkan, Mehmet Tezcan

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and carries poor prognosis. Despite advances in therapy, no significant increase in survival has been achieved for GBM patients. These tumors inevitably recur in the majority of patients, and the therapeutic options for recurrent tumors are limited. GBMs are aggressive, f...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Nataša Vidović, Dragan Dimov

Oxidative stress, as one of the pathophysiological mechanisms involved in the reduction of myocardial contractility, stimulates the proliferation of cardiac fibroblasts and the activation of matrix metalloproteinases, which leads to extracellular matrix remodeling. Left ventricular hypertrophy (LVH) is a well-known independent risk factor for cardi...

By Sandra Šarić, Tatjana Cvetković, Dejan Petrović, Valentina Mitić, Sanja Stojanović, Vladana Stoiljković, Marina Deljanin-Ilić

The aim of the research was to investigate prognostic factors in patients with resected colorectal liver metastases (CLMs) after biological and chemotherapy, which made initially unresectable disease suitable for resection. Sixty-six patients with resected CLMs, operated after induction bio-chemotherapy with bevacizumab + FOLFOX4, treated at the Cl...

By Miljana Džunić, Ivan Petković, Ana Cvetanović, Ivica Pejčić, Svetislav Vrbić, Saša Dinić

Teeth are biological markers of maturity, and their eruption into the oral cavity is an essential milestone in an individual's life. Multiple factors have been considered to play a role in the pattern of tooth eruption, including dental caries, fluorides and congenital conditions such as Down's syndrome. The aim of the paper was to determine the ti...

By Varshini Marimuthu, Pushparaja Shetty

Achilles tendon injuries most commonly occur in athletes, but also in the middle-aged population practicing recreational sports. The aetiology of injury and disease of the Achilles tendon has not been completely clarified. While acute injury can be attributed to trauma, research showed that a chronic degenerative process is present in most ruptures...

By Mihajlo Mitrović, Dražen Jelača, Ivana Mitrović