The dissolution test is a simple and important in vitro method for assessing the bioequivalence, which aims to compare the bioavailability of generic and branded drugs. It implies the use of a proper apparatus (usually pharmacopoeially defined) in which the dosage form is dissolved, and the dissolution process itself is monitored/quantified using a...

By Ana Marković, Miroslava Spasić, Vesna Savić, Slavica Sunarić, Marija Tasić-Kostov

Infective endocarditis (IE) is an important clinical disease in children with a mortality rate of 11.6%. Prophylaxis with antibiotics is one of the most commonly used methods in children at risk of IE; therefore, the evaluation of antibiotic resistance seems necessary in view of its increasing trend. This study aimed to determine the antibiotic sus...

By Morva Moudi, Nilgoon Pasdar, Kazem Babazadeh, Zahra Shahandeh, Farahnaz Sadighian

The aim of the study was to analyze and compare consultation lengths in Emergency Medical Service (EMS) Belgrade ambulatory clinic which relates to patient age, gender, existing diagnoses and prescribed treatment (therapy or referral to another healthcare institution). We analyzed the data from the electronic database on consultation lengths from o...

By Slavoljub Živanović, Miloranka Petrov-Kiurski

It is of particular importance to use validated questionnaires to remove fear of needles and blood collection, as this public health problem has been observed in a large number of patients and may inadequately affect medical healthcare. The aim of the study was to conduct a research on the reliability of the questionnaire on the fear of blood sampl...

By Suzana Milutinović, Ana Stanković, Sunčica Ivanović, Sanja Trgovčević, Tatjana Kilibarda

The infectious factor is etiological in the caries development. Early colonization of S. mutans is considered as a key point; another important caries-associated microorganism is Lactobacillus, which colonizes carious lesions later. Ecological shifts in the dental plaques against the background of weakened local immunity increase their cariogenicit...

By Loban' Andriivna, Faustova Oleksiivna, Chereda Volodymyrivna, Ananieva Mykolaivna

Caring for COVID-19 patients at home is a global challenge. This study aimed to review recommendations put forward on home care for patients with suspected COVID-19 presenting with mild clinical features. This is a review of the scientific literature covering COVID-19 and home care from the medical electronic databases such as PubMed, ProQuest, Goo...

By Javad Dehghannezhad, Vahid Zamanzadeh, Damanabad Heydarpoor, Hadi Hassankhani, Malcolm Boyle, Abbas Dadashzadeh

The apprehensiveness for the knowledge vacuum on existential threat of nasal carriage of pvl+ healthcare-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) strains amongst subjects in hospitals have led us to pursue a grasp on the constellation of staphylococcal cassette chromosome mec (SCCmec) types and pvl gene among mecA positive MRSA...

By Adeiza Suleiman, Onaolapo Ademola, Olayinka Olalekan

Aluminum phosphide, known as "rice tablet" (RT), is a common cause of suicide in adult women in Iran, with a high rate of lethal outcome. We report a patient with RT toxicity, with a complex syndrome of hepatic failure, renal failure, Brugada electrocardiography (ECG) patterns, and pleuropericardial effusion. The patient received conventional manag...

By Feridoun Sabzi, Aghigh Heydari, Reza Moghaddam, Mohammad Rouzbahani, Atefeh Asadmobini

This study compares the acute cardiovascular responses of rowing athletes during a rowing test in laboratory and field conditions in order to identify possible differences between the two types of the rowing tests. Six male rowers completed the rowing tests, using the Concept2 rowing paddle at the laboratory and a skiff in the water. Heart rate, bl...

By Nikolaos Coutlianos, Nikolaos Panolias, Milena Tomović, Serafeim Alexiou

The aim of the research was to investigate prognostic factors in patients with resected colorectal liver metastases (CLMs) after biological and chemotherapy, which made initially unresectable disease suitable for resection. Sixty-six patients with resected CLMs, operated after induction bio-chemotherapy with bevacizumab + FOLFOX4, treated at the Cl...

By Miljana Džunić, Ivan Petković, Ana Cvetanović, Ivica Pejčić, Svetislav Vrbić, Saša Dinić