Single Center Experience Study with Pembrolizumab in Patients with BRAF Mutant Negative Metastatic Melanoma
The aim of the paper was to determine the efficacy, toxicity and progression free survival with anti-PD-1 immunotherapy pembrolizumab in BRAF wild type metastatic melanoma patients with good performance status (ECOG PS 0-1). From February 2017 to April 2018, 17 patients with BRAF mutant wild type metastatic melanoma were enrolled in the study. Only...
By Ivica Pejčić, Ivan Petković, Ana Cvetanović, Irena Conić
Error Analysis for Determination of Accuracy of Johnson’s Formula, Dare’s Formula and Mother's Opinion for the Estimation of Birth Weight: Results of an Iranian Cross‐Sectional Study
Accurate fetal weight estimation is important for the management of birth. According to the existing literature, none of the clinical techniques is superior to any other. This study aimed to compare error analysis for the determination of the accuracy of Johnson’s formula, Dare’s formula and mother's opinion for the estimation of birth ...
By Somayeh Alirezaei, Elham Azmoude, Asma Ghaderi
Evaluation of Prognostic Factors Involved in Seroma Formation after Radical Surgery for Breast Cancer
Seromas belong to common postoperative complications in breast surgery, with the prevalence rate from 3% to 60%.Our aim in this paper was to establish the factors most significant in the occurrence of seroma after radical surgery for breast cancer.The study employed a prospective non-randomized design and took place at the General Surgery Clinic, C...
By Miodrag Djordjević, Toplica Bojić, Lidija Djordjević, Dragana Budjevac, Nebojša Djordjević, Nebojša Ignjatović, Ivan Pešić, Ana Cvetanović, Mladjan Golubović, Jovan Janić, Jovan Janić, Jovan Janić
The Oil Content of Wild Fruits from Different Plant Species Obtained by Conventional Soxhlet Extraction Technique
Oils from wild fruits have gained attention due to the presence of the wide variety of natural bioactive lipid components (essential polyunsaturated fatty acids, phytosterols, lipid-soluble vitamins), which have positive effects on human health. The present study describes the extraction of oils from fruits of different plant species, Sambucus nigr...
By Milica Stanković, Svetolik Maksimović, Vanja Tadić, Ivana Arsić
The Impact of Resistance Training Program on the Muscle Strength and Bone Density in Adolescent Athletes
Strength training and other modes of physical activity may be beneficial in osteoporosis prevention by maximizing bone mineral accrual in childhood and adolescence. This study focuses on the impact of the nine-month long program of resistant exercises with different level of external loads (low, middle and high) on the lower limbs explosive strengt...
By Saša Bubanj, Milorad Mitković, Tomislav Gašić, Sanja Mazić, Ratko Stanković, Dragan Radovanović, Borislav Obradović, Goran Šekeljić, Milovan Stamatović, Jovan Marković, Slavoljub Uzunović
Application of the New Self-dynamisable Internal Fixator in the Treatment of Femoral Shaft Fractures
The aim of this study was to present the results of one original method application in internal fixation of long bones. The series of 27 patients with unilateral fractures of femoral shaft was analyzed. According to AO classification, 21 fractures were classified as 32A, five as 32B, and one as 32C type. Original diaphyseal self-dynamisable interna...
By Milan Mitković, Saša Milenković, Ivan Micić, Predrag Stojiljković, Igor Kostić, Slobodan Milenković, Dražen Jelača, Milorad Mitković
Genetic Variability of Tumor Necrosis Factor Receptors Type I and II in Lymphoproliferative Diseases in the Serbian Population
TNF-alpha and LT-alpha are involved in the pathogenesis of established lymphoproliferative diseases. Both molecules bind to TNFRI and TNFRII. TNFRI is the major mediator of the TNF pro-apoptotic and proliferative effects and TNFRII might enhance these effects. TNF receptors I and II are normally present on hematopoetic cells. TNFR II is characteris...
By Tatjana Jevtović-Stoimenov, Danica Marković, Milena Despotović, Dušica Pavlović, Gordana Kocić
Erratum
ERRATUM The authors of this paper regret to advise that the following corrections are required in order to rectify copyright infringement of the Morisky Medication Adherence scale (MMAS-8) – a retroactive license has been obtained. Article “Medication adherence in outpatients with arterial hypertension” authored by Jelena Lali...
Contribution to the History of Serbian Medicine: Ten Years from the Introduction of Clostridium difficile into Microbiological Diagnostics in Serbia
In Serbia, the first isolates ofC. difficilewere isolated in the Public Health Institute (PHI), Center for Microbiology in Niš, at the end of 2005.The National Reference Laboratory for Anaerobic Infections (NRLA) in PHI Niš confirmed the toxigenic strains that caused the first three registered hospital epidemics in Serbia, in 2006 at ...
By Predrag Stojanović, Branislava Kocić, Gorana Dragovac, Marina Randjelović, Vukica Pantović, Zorica Mitić, Kristina Stojanović
D2-40 Immunoreactivity of Lymphatic Vessels Endothelium and Representation of Lymphatic Vessels in the Liver of Human Fetuses of Different Gestational Age
In the reference literature, there are a few studies on the development of the lymphatic system in the liver, especially human. This study aims to establish the presence, time of appearance, distribution and representation of expression D2-40 molecule – a marker of lymph vessels endothelial cells during the fetal period of the human liver dev...
By Marko Jović, Ivan Nikolić, Vera Todorović, Aleksandar Petrović, Vladimir Petrović, Tijana Denčić