SummaryThe metabolic pathways of chlorpromazine (CPZ) toxicity were tracked by assessing oxidative/nitrosative stress markers. The main objective of the study was to test the hypothesis that agmatine (AGM) prevents oxidative/nitrosative stress in the liver of Wistar rats 15 days after administration of CPZ. All tested substances were administered i...

By Bratislav Dejanović, Ivana Stevanović, Milica Ninković, Ivana Stojanović, Irena Lavrnja, Tatjana Radičević

SummaryThe aim of the study was to analyze perioperative parameters as well as early postoperative period of patients with trochanteric fractures nailing in relation to the fracture stability.The prospective study included 46 patients with trochanteric fractures fixed with the third generation cephalomedullary nail. Two groups were formed - stable ...

By Nina Đorđević, Miloš Stanojlović, Saša Milenković, Predrag Stojiljković, Mirjana Kocić, Ivan Golubović

Summary The aim of the paper was to develop and validate a scale for estimating the likelihood of a nurse student to become a competent nurse. Admitting students to nursing schools without assessing their personal characteristics has led to serious consequences, including low quality of nursing care. Early detection of students who are at risk of a...

By Abbas Heydari, Hossein Kareshki, Mohammad Reza Armat

Summary Aortic dissection is a quite rare but serious condition, often associated with a very high mortality rate; it is manifested by sudden chest pain and acute hemodynamic compromise. In the presented review, a case of an ascending aortic dissection with the lethal outcome is been shown. A healthy man with no past history of illness suddenly fel...

By Sanja Stojanović, Marina Deljanin Ilić, Stevan Ilić, Bojan Ilić, Milovan Stojanović, Dejan Petrović

Summary Herein we present a 25-year-old female patient with tetralogy of Fallot (TOF). This congenital heart defect is not very common, but it is the most common one among cyanotic heart defects. Treatment of the patients with TF is surgical, with palliative or curative (corrective) intent. Our patient underwent palliative surgery, definitive corre...

By Jovana Cvetković, Dragan Đ Đorđević, Milan Šljivić, Marina Deljanin Ilić

Summary The aim of this study was to analyze the reasons why the guidelines for post-splenectomy vaccination are not being followed. Considering that vaccination reduces the risk of overwhelming post-splenectomy infection, it is important to determine the reasons for inadequate vaccination after splenectomy. Our research was a qualitative study bas...

By Marko Tanasković, Bozidar Odalović, Slobodan Janković, Nedim Hamzagić

SummaryConsidering a large number of pathogen factors that enable high virulence of a microorganism such as Staphylococcus aureus (S. aureus), it is essential to see them through the continuous adaptation to the newly acquired mechanisms of the host immune response and efforts to overcome these, allowing the bacteria a perfect ecological niche for ...

By Biljana Miljković-Selimović, Marina Dinić, Jovan Orlović, Tatjana Babić

Summary Salicylic acid is a phytochemical with beneficial effects on human well-being. Salicylic acid is a phenolic compound and is present in various plants where it has a vital role in protection against pathogenic agents. Natural sources include fruits, vegetables and spices. The most famous and defined effect of salicylic acid is prostaglandin ...

By Pavle Randjelović, Slavimir Veljković, Nenad Stojiljković, Dušan Sokolović, Ivan Ilić, Darko Laketić, Dušica Randjelović, Nebojša Randjelović

Summary The present study aimed to examine the factors affecting the possible changes in serum fetuin-A in patients with preeclampsia (PE). The examined factors included the parameters of insulin resistance (IR) [(insulin sensitivity (HOMA%S), insulin resistance (HOMA2IR), and beta-cell functions (HOMA%B)], which were calculated using the HOMA2 cal...

By Hussein Kadhem Al-Hakeim, Roaa Ali Muhammed Ali

SummarySmoking has many harmful effects on human body. It is well known that smoking is one of the most important risk factors for cardiovascular diseases. Though the ingredients from cigarette smoke stimulate the release of vasoconstrictor and reduce the release of vasodilator substances, the goal of this study was to investigate the acute effects...

By Ana Mrkaić, Suzana Branković, Pavle Randjelović, Milica Veljković, Ivan Pavlović, Mirjana Radenković