The application of anthracycline and trastuzumab in adjuvant breast cancer treatment approach has significantly improved the survival of patients, but also carries the risk of cardiotoxicity that is manifested by reducing the ejection fraction of the heart. The aim of the study was to investigate the effect of cumulative anthracycline dose in combi...

By Ivana Krstić, Marina Deljanin Ilić, Svetislav Vrbić, Ivica Pejčić

Leech therapy is likely to cause symptomatic relief in migraine headache sufferers, but there is little clinical data in this field. This study aimed to investigate the effectiveness of leech therapy in the management of migraine headaches. This is a quasi-experimental pilot study with a three-month post-treatment follow-up. Twenty-six patients wit...

By Mahmoud Bakhshi, Babak Jalalian, Maryam Valian, Saeide Shariati, Tahere Saeidi, Hossein Ranjbar

Peutz-Jeghers syndrome (PJS) is a rare genetic disorder with autosomal-dominant pleiotropic inheritance, variable penetrance and characteristic signs of the disease that predisposes persons to increased risk of developing cancer, particularly in the gastrointestinal tract and the breast. Due to genetic nature of disease, in the familial Peutz-Jeghe...

By Marijola Mojsilović, Vuka Katić, Ivan Ilić, Biljana Radovanović, Bratislav Petrović, Miodrag Lazić, Marijana Krstić

The pathophysiology of periapical lesions (PLs) is under control of pro-inflammatory and anti-inflammatory (mainly immunoregulatory) cytokines. We have recently established mesenchymal stem cells (MSCs) from PLs and showed their suppressive effects on the production of proinflammatory cytokines from PLs inflammatory cells (ICs). In this work we stu...

By Milan Marković, Sergej Tomić, Jelena Djokić, Miodrag Čolić

The aim of the paper was to investigate the tissue response to the implantation of "Endomethasone" (Septodont) in artificially prepared defect in the rat mandible. Sixteen Wistar male rats were used for the experiment. After anesthesia, a defect between the midline and the mental foramen of the left mandible was made (diameter 1.4 mm, 1.6 mm depth)...

By Marija Nikolić, Jovanka Gašić, Aleksandar Mitić, Jelena Popović, Aleksandra Radovanović, Radomir Barac

For more than three decades, assisted reproductive techniques (ART) have been used as effective treatments to overcome infertility. Since then, numerous studies have been focused on different aspects of long-term health and development of children born after assisted conception. The aim of this paper is to summarize new data on multiple pregnancy a...

By Milena Milićević, Srećko Potić

Milk contains plenty of enzymatic and non-enzymatic antioxidant components that probably account for the vital antioxidant protection of the infants at early stages of life against the development of complications induced by oxygen free radicals. Indigenous milk enzymes play a key role in regulating lactogenesis, including active involution of mamm...

By Jelena Živković, Slavica Sunarić, Nataša Trutić, Marko Denić, Gordana Kocić, Tatjana Jovanović

Publication ethics has always been a major concern of chief editors and members of editorial boards of journals. Therefore, the current study intends to investigate ethical issues in sticking to publication ethics in major medical journals in Iran. This descriptive analytical study was conducted on Iranian medical journals approved as “scient...

By Mohsen Koushan, Akbar Pejhan, Nematullah Shomoossi, Azam Shomoossi

The aim of the survey was to present the clinical course and surgical treatment of the first case of human ocular dirofilariosis on the territory of the city of Niš, in the southeast Serbia. Male patient, 57 years old, visited an ophthalmologist because of extreme swelling and redness of the eyelids of the right eye, scratches and pain in hi...

By Marija Trenkić Božinović, Branislav Tomašević, Simona Gabrielli, Suzana Otašević, Aleksandar Petrović, Gabriella Cancrini, Aleksandar Tasić, Milan Trenkić

The aim of this paper was to determine the trend of diseases and epidemiological characteristics of viral antigen carrying of hepatitis B for better implementation of prevention and control of the disease activity. The annual reports, reports of diseases - deaths from infectious diseases, epidemiological survey of the Public Health Institute (IPH) ...

By Marina Kostić, Biljana Kocić, Nataša Rančić