Retinitis pigmentosa (RP) is a diverse group of inherited retinal diseases characterized by the gradual degeneration of rod and cone photoreceptors in the retina. RP is primarily inherited, with numerous genetic mutations implicated in its pathogenesis. The aim of this study was to summarize the findings of studies related to genes implicated in re...

By Olivia Narváez, Zerón Mendieta, Orlando Torres, Magally Escobar, Martha Trujillo-Güiza

Rheumatoid arthritis (RA) is a systemic autoimmune disease that can cause destructive joint disease and progressive disability. The diagnosis of RA is based on laboratory and clinical evidence, which includes the analysis of inflammatory markers, hematological, and biochemical parameters. Fifty patients diagnosed with RA without methotrexate (MTX) ...

By Maja Mitrašinović-Brulić, Ema Maslo, Muhamed Fočak, Damir Suljević

Pre-eclampsia is a major cause of perinatal mortality. Glutamate plays a critical function in the promotion of a healthy pregnancy. Therefore, the aim of this study was to determine the extent of the correlation between pre-eclampsia and 4-hydroxyglutamate acid. This is a case-control study that was conducted on a sample of 100 pregnant women in th...

By Noor Fawzi, Sheikh Al

Venomous snakebites in Serbia are neither too frequent nor extremely dangerous. Nevertheless, some can lead to complications or even death. On December 24, 2023, a young man was admitted to hospital after being bitten by a snake, believed to be Vipera ammodytes. He was in a state of shock, unconscious, with unmeasurable blood pressure. Having recei...

By Slađana Pavić, Sonja Nikolić

Burns represent one of the leading causes of morbidity and mortality in children. Aim. Aim of this review is to gain better understand of the pathophysiological changes and assessment of the severity of burn injuries in different ages of pediatric patients, which may help in early implementation of appropriate therapeutic procedures and improvement...

By Vesna Marjanović

Breast cancer (BC) represents a globally significant health issue, with incidence rates varying worldwide. Radiotherapy is crucial in treating BC, however, it can cause adverse effects, including skin reactions. The aim of this research was to evaluate the impact of two different radiotherapy fractionation regimens on the occurrence and severity of...

By Milica Radić, Andrija Jović, Ana Cvetanović, Ivan Petković, Dane Krtinić, Katarina Krasić, Sandra Radenković, Slavica Stojnev, Irena Conić

The emergence of the COVID-19 pandemic has underscored the critical importance of accurate and reliable methods for the early detection and management of cases. Traditional approaches to COVID-19 diagnosis often rely on binary classification methods, which may limit their accuracy and robustness. In this study, we propose a novel approach that leve...

By Affaf Khaouane, Latifa Khaouane, Samira Ferhat, Salah Hanini

Multiple sclerosis (MS) is a chronic, autoimmune demyelinating disease of the central nervous system. The association of vitamin D deficiency, sun exposure, and higher incidence of multiple sclerosis has been known for long, and a number of studies have confirmed anti-inflammatory and neuroprotective properties of vitamin D. Vitamin D receptor (VDR...

By Lazar Bajić, Dejan Savic, Nikola Krstić, Ana Andrejević, Andrija Rančić, Miljana Mladenović, Tatjana Jevtovic Stoimenov

Wernicke encephalopathy is a rare acute/subacute neurological disorder, commonly caused by prolonged thiamine deficiency in patients who chronically consume alcohol. According to the Caine classification criteria, the clinical diagnosis of this encephalopathy involves at least two of the following four signs: nutritional deficiency, oculomotor dysf...

By Aleksandra Lučić-Prokin, Vladimir Galić, Timea Kokai-Zekić, Vedran Žigić

Zinc is a trace element involved in insulin metabolism, including its production, storage, and release. Selenium is regarded as a vital micronutrient for humans. It participates in insulin signaling and control. Zinc and selenium may be possibly linked to insulin resistance; however, these relationships have not been well investigated. Therefore, w...

By Fahad Hammadi, Hamdan Bader, Al-Mayah Sharhan