Salicylic acid is a phytochemical with beneficial effects on human well-being. Salicylic acid is a phenolic compound and is present in various plants where it has a vital role in protection against pathogenic agents. Natural sources include fruits, vegetables and spices. The most famous and defined effect of salicylic acid is prostaglandin synthesi...

By Pavle Randjelović, Slavimir Veljković, Nenad Stojiljković, Dušan Sokolović, Ivan Ilić, Darko Laketić, Dušica Randjelović, Nebojša Randjelović

Smoking has many harmful effects on human body. It is well known that smoking is one of the most important risk factors for cardiovascular diseases. Though the ingredients from cigarette smoke stimulate the release of vasoconstrictor and reduce the release of vasodilator substances, the goal of this study was to investigate the acute effects of smo...

By Ana Mrkaić, Suzana Branković, Pavle Randjelović, Milica Veljković, Ivan Pavlović, Mirjana Radenković

Many of the children referred to the emergency complain of head trauma. Children usually require sedition to reduce their failure and fear because of high activity and fear of performing computed tomography (CT). Dexmedetomidine and Midazolam belong to short-acting drugs for this purpose. This study aimed to compare the effect of the above mentione...

By Adel Hosseini, Shamila Noori, Abolfazl Mostafavi, Ali Sharami, Seyyed Abbas Hashemi, Hojjat Derakhshanfar, Farzad Bozorgi

Economic evaluations in health economics are analytical methods used for the analysis of costs and consequences of two or more alternative health programs or interventions. These analyses involve identification, measurement, evaluation and comparison of costs and consequences. Whenever there are two alternative health programs or treatments that le...

By Vladica Veličković, Aleksandar Višnjić, Jovan Mihajlović

Spastic cerebral palsy (CP) is the most common type of CP. Up to 80% of all individuals with cerebral palsy suffer from some degree of spasticity. Spasticity adversely affects muscles and joints of the extremities, causing abnormal movements, and it is especially harmful in growing children. Several methods have been developed and used to assess sp...

By Lidija Dimitrijević, Hristina Čolović, Marija Spalević, Anita Stanković, Dragan Zlatanović, Bratislav Cvetković

Quality of life (QOL) in families can be affected when a child has cerebral palsy (CP). The aim of this research was to determine the effect of a child’s disability on the mother’s quality of life by comparing mothers of children with CP and mothers of normal children. Two sample groups were chosen from a total of 42 mothers to answer a...

By Samira Borzoo, Mansoureh Nickbakht, Mehrdad Jalalian

The main issue in patients with pulmonary tuberculosis (PTB) represents the impossibility of the host immune response to express bactericidal function and the sterilization of lesions depends exclusively on the specific antimicrobial chemotherapy. In order to investigate the value of acute-phase inflammatory response markers in patients with newly ...

By Milan Radović, Tatjana Pejčić, Ivana Stanković, Lidija Ristić, Milan Rančić, Zorica Ćirić

The study of features of pharmacodynamics of a new analgesic is an important and urgent task of modern pharmacology. These data allow us to clarify the nosology for application of an analgesic and to create a theoretical background to optimize its use. An effect mediated by the transient receptor potential cation channel, subfamily V, member 1 (TRP...

By Oleh Yadlovskyi, Tatiana Bukhtiarova, Lyudmila Bobkova, Irina Tatianshenko, Igor Monchak, Andrew Khayrulin

The aim of this study was to investigate the exogenous agmatine influence on nitrosative and oxidative stress parameters in acute phase of multiple sclerosis (MS) experimental model, experimental autoimmune encephalomyelitis (EAE). EAE was induced by subcutaneous injection of myelin basic protein (50 μg per animal). Sprague-Dawley rats were divi...

By Ivana Stojanović, Srđan Ljubisavljević, Ivana Stevanović, Slavica Stojnev, Radmila Pavlović, Dušan Sokolović, Aleksandar Petrović, Dušica Pavlović, Tatjana Cvetković

Reproductive health implies that people are able to have a responsible, satisfying and safe sex life and that they have the capability to reproduce and the freedom to decide about it. It is directly conditioned by social, cultural and behavior factors. One in every five people in the world is an adolescent, and 85% of them live in developing countr...

By Olivera Radulović, Slađana Babić, Milena Veljković, Ana Stefanović, Čedomir Šagrić, Katarina Bulatović