The sequence of precursor lesions for squamous cell carcinoma may be hyperplasia-metaplasia-dysplasia-carcinoma in situ. The aim of this study was to perform a karyometric analysis of squamous metaplasia, moderate dysplasia and squamous cell lung carcinoma. Bronchoscopic biopsies of normal mucosa in chronic bronchitis patients (n = 10), squamous me...

By Žaklina Mijović, Zoran Pešić, Nikola Živković, Tijana Denčić, Ana Ristić Petrović, Slavica Stojnev

Uvae ursi folium (Arctostaphylos uva ursi, Ericaceae) is the best known and most widely used herbal urinary antiseptic. In traditional medicine, other Ericaceae species are also used for the treatment of urinary tract infections. The present study investigates antimicrobial activity of five species of Ericaceae family native to the Balkan Peninsula...

By Dragana Pavlović, Branislava Lakušić, Dušanka Kitić, Milica Milutinović, Milica Kostić, Bojana Miladinović, Nada Kovačević

Ultrastructure of adhesive bond is a significant indicator of the efficiency of the bond between material and dental tissue. Bonding between composite and hard dental tissue is also most commonly assessed by measuring bonding strength or by absence of marginal gap along restoration interface. The aim of this investigation was to estimate ultrastruc...

By Stefan Dačić, Aleksandar Mitić, Jelena Popović, Dragica Simonović Dačić, Marko Igić

Spastic cerebral palsy (CP) is the most common type of CP. Up to 80% of all individuals with cerebral palsy suffer from some degree of spasticity. Spasticity adversely affects muscles and joints of the extremities, causing abnormal movements, and it is especially harmful in growing children. Several methods have been developed and used to assess sp...

By Lidija Dimitrijević, Hristina Čolović, Marija Spalević, Anita Stanković, Dragan Zlatanović, Bratislav Cvetković

Quality of life (QOL) in families can be affected when a child has cerebral palsy (CP). The aim of this research was to determine the effect of a child’s disability on the mother’s quality of life by comparing mothers of children with CP and mothers of normal children. Two sample groups were chosen from a total of 42 mothers to answer a...

By Samira Borzoo, Mansoureh Nickbakht, Mehrdad Jalalian

The main issue in patients with pulmonary tuberculosis (PTB) represents the impossibility of the host immune response to express bactericidal function and the sterilization of lesions depends exclusively on the specific antimicrobial chemotherapy. In order to investigate the value of acute-phase inflammatory response markers in patients with newly ...

By Milan Radović, Tatjana Pejčić, Ivana Stanković, Lidija Ristić, Milan Rančić, Zorica Ćirić

In search for new and promising coumarin compounds as HIV-1 integrase inhibitors, chemoinformatic methods like quantitative structure-activity relationships (QSAR) modeling and molecular docking have an important role since they can predict desired activity and propose molecule binding to enzyme. The aim of this study was building of QSAR models fo...

By Jovana Veselinović, Aleksandar Veselinović, Andrey Toropov, Alla Toropova, Ivana Damnjanović, Goran Nikolić

Isoform 2 of calsequestrin (CASQ2) is the main calcium-binding protein of sarcoplasmic reticulum (SR), expressed both in cardiac and in skeletal muscles. CASQ2 acts as an SR calcium (Ca2+) sensor and regulates SR Ca2+ release via interactions with triadin, junctin, and the ryanodine receptor. Various mutations of the csq2 gene lead to altered Ca2+ ...

By Rigers Bakiu

The aim of this study was to investigate the exogenous agmatine influence on nitrosative and oxidative stress parameters in acute phase of multiple sclerosis (MS) experimental model, experimental autoimmune encephalomyelitis (EAE). EAE was induced by subcutaneous injection of myelin basic protein (50 μg per animal). Sprague-Dawley rats were divi...

By Ivana Stojanović, Srđan Ljubisavljević, Ivana Stevanović, Slavica Stojnev, Radmila Pavlović, Dušan Sokolović, Aleksandar Petrović, Dušica Pavlović, Tatjana Cvetković

Reproductive health implies that people are able to have a responsible, satisfying and safe sex life and that they have the capability to reproduce and the freedom to decide about it. It is directly conditioned by social, cultural and behavior factors. One in every five people in the world is an adolescent, and 85% of them live in developing countr...

By Olivera Radulović, Slađana Babić, Milena Veljković, Ana Stefanović, Čedomir Šagrić, Katarina Bulatović