The presence of diabetes mellitus leads to a decrease in life quality in all domains. The aim of our study was to evaluate the quality of life (QOL) in diabetic patients and the factors affecting it in type 2 diabetic mellitus patients. We conducted a cross-sectional study that included 86 patients with type 2 diabetes mellitus, in the territory of...

By Ana Spasić, Radmila Veličković Radovanović, Aleksandra Catić Đorđević, Nikola Stefanović, Tatjana Cvetković

The sequence of precursor lesions for squamous cell carcinoma may be hyperplasia-metaplasia-dysplasia-carcinoma in situ. The aim of this study was to perform a karyometric analysis of squamous metaplasia, moderate dysplasia and squamous cell lung carcinoma. Bronchoscopic biopsies of normal mucosa in chronic bronchitis patients (n = 10), squamous me...

By Žaklina Mijović, Zoran Pešić, Nikola Živković, Tijana Denčić, Ana Ristić Petrović, Slavica Stojnev

Medicinal herbs and their mixtures, which are widely used for prevention and treatment of some disease, can also present health risks due to the presence of toxic metals such as Pb and Cd. The application of different agrotechnical practices during plant growing season, as well as the process of circulation of substances in nature, may be the cause...

By Biljana Kaličanin, Dragan Velimirović, Ivana Arsić, Sofija Đorđević

Uvae ursi folium (Arctostaphylos uva ursi, Ericaceae) is the best known and most widely used herbal urinary antiseptic. In traditional medicine, other Ericaceae species are also used for the treatment of urinary tract infections. The present study investigates antimicrobial activity of five species of Ericaceae family native to the Balkan Peninsula...

By Dragana Pavlović, Branislava Lakušić, Dušanka Kitić, Milica Milutinović, Milica Kostić, Bojana Miladinović, Nada Kovačević

Ultrastructure of adhesive bond is a significant indicator of the efficiency of the bond between material and dental tissue. Bonding between composite and hard dental tissue is also most commonly assessed by measuring bonding strength or by absence of marginal gap along restoration interface. The aim of this investigation was to estimate ultrastruc...

By Stefan Dačić, Aleksandar Mitić, Jelena Popović, Dragica Simonović Dačić, Marko Igić

Spastic cerebral palsy (CP) is the most common type of CP. Up to 80% of all individuals with cerebral palsy suffer from some degree of spasticity. Spasticity adversely affects muscles and joints of the extremities, causing abnormal movements, and it is especially harmful in growing children. Several methods have been developed and used to assess sp...

By Lidija Dimitrijević, Hristina Čolović, Marija Spalević, Anita Stanković, Dragan Zlatanović, Bratislav Cvetković

The aim of our study was to analyze the changes of connective tissue sheaths of epi-, peri- and endoneurium of sural nerve during aging. The study was conducted on sural nerve samples of 10 cases aged 9-80 years. The specimens were embedded in paraffin using standard procedures, after which 5-μm-thick cross-sections of nerve trunks were made and...

By Braca Kundalić, Slađana Ugrenović, Ivan Jovanović, Natalija Stefanović, Vladimir Petrović, Jasen Kundalić, Miljana Pavlović, Vladimir Antić

In search for new and promising coumarin compounds as HIV-1 integrase inhibitors, chemoinformatic methods like quantitative structure-activity relationships (QSAR) modeling and molecular docking have an important role since they can predict desired activity and propose molecule binding to enzyme. The aim of this study was building of QSAR models fo...

By Jovana Veselinović, Aleksandar Veselinović, Andrey Toropov, Alla Toropova, Ivana Damnjanović, Goran Nikolić

The aim of the paper was to show the diagnostic and therapeutic approaches to a patient suffering from osteomalacia, as well as differential diagnosis with osteoporosis. Osteomalacia (OM) is a metabolic disease of bones which appears as a result of defective mineralization of newly formed bone matrix in adults. Diagnosis of disease may represent a ...

By Nela Živković, Sonja Stojanović

Isoform 2 of calsequestrin (CASQ2) is the main calcium-binding protein of sarcoplasmic reticulum (SR), expressed both in cardiac and in skeletal muscles. CASQ2 acts as an SR calcium (Ca2+) sensor and regulates SR Ca2+ release via interactions with triadin, junctin, and the ryanodine receptor. Various mutations of the csq2 gene lead to altered Ca2+ ...

By Rigers Bakiu