Smoking has many harmful effects on human body. It is well known that smoking is one of the most important risk factors for cardiovascular diseases. Though the ingredients from cigarette smoke stimulate the release of vasoconstrictor and reduce the release of vasodilator substances, the goal of this study was to investigate the acute effects of smo...

By Ana Mrkaić, Suzana Branković, Pavle Randjelović, Milica Veljković, Ivan Pavlović, Mirjana Radenković

Herein we present a 25-year-old female patient with tetralogy of Fallot (TOF). This congenital heart defect is not very common, but it is the most common one among cyanotic heart defects. Treatment of the patients with TF is surgical, with palliative or curative (corrective) intent. Our patient underwent palliative surgery, definitive correction, a...

By Jovana Cvetković, Dragan Đ Đorđević, Milan Šljivić, Marina Deljanin Ilić

Many of the children referred to the emergency complain of head trauma. Children usually require sedition to reduce their failure and fear because of high activity and fear of performing computed tomography (CT). Dexmedetomidine and Midazolam belong to short-acting drugs for this purpose. This study aimed to compare the effect of the above mentione...

By Adel Hosseini, Shamila Noori, Abolfazl Mostafavi, Ali Sharami, Seyyed Abbas Hashemi, Hojjat Derakhshanfar, Farzad Bozorgi

Economic evaluations in health economics are analytical methods used for the analysis of costs and consequences of two or more alternative health programs or interventions. These analyses involve identification, measurement, evaluation and comparison of costs and consequences. Whenever there are two alternative health programs or treatments that le...

By Vladica Veličković, Aleksandar Višnjić, Jovan Mihajlović

The main issue in patients with pulmonary tuberculosis (PTB) represents the impossibility of the host immune response to express bactericidal function and the sterilization of lesions depends exclusively on the specific antimicrobial chemotherapy. In order to investigate the value of acute-phase inflammatory response markers in patients with newly ...

By Milan Radović, Tatjana Pejčić, Ivana Stanković, Lidija Ristić, Milan Rančić, Zorica Ćirić

The study of features of pharmacodynamics of a new analgesic is an important and urgent task of modern pharmacology. These data allow us to clarify the nosology for application of an analgesic and to create a theoretical background to optimize its use. An effect mediated by the transient receptor potential cation channel, subfamily V, member 1 (TRP...

By Oleh Yadlovskyi, Tatiana Bukhtiarova, Lyudmila Bobkova, Irina Tatianshenko, Igor Monchak, Andrew Khayrulin

Emergency hormonal contraception is used to prevent unintended pregnancy postcoitally. The mechanism of action of the most frequently used hormonal preparations for emergency contraception, levonorgestrel (LNG) and ulipristal acetate (UPA), is still not fully known, but clinical trials indicate that they act by inhibiting or delaying ovulation. LNG...

By Jelena Milosavljević, Katarina Ilić, Dušanka Krajnović

Osteoporosis is a chronic disease with increasing incidence that predominantly occurs in female population. There are evidences that bisphosphonates, selective estrogen receptor modulators, denosumab, teriparatide and strontium renalate, prevent vertebral fractures while alendronate, risedronate, zoledronic acid, denosumab and strontium renalate pr...

By Ivana Tadić, Ljiljana Tasić, Nada Vujašinović Stupar, Katarina Ilić, Dejan Stevanović

Symptoms of bladder dysfunction are significant public health problem due to their prevalence, morbidity and treatment costs. Most stem from bladder control problem which is governed by the brain, yet we know little about CNS and bladder. Advances in brain imaging technology have brought new insight in how brain works in different bladder diseases ...

By Staša Tadić

Reproductive health implies that people are able to have a responsible, satisfying and safe sex life and that they have the capability to reproduce and the freedom to decide about it. It is directly conditioned by social, cultural and behavior factors. One in every five people in the world is an adolescent, and 85% of them live in developing countr...

By Olivera Radulović, Slađana Babić, Milena Veljković, Ana Stefanović, Čedomir Šagrić, Katarina Bulatović