New frontiers of target therapy in oncology: acute promyelocytic leukemia
By introduction of all-trans retinoic acid (ATRA) in de novo acute promyelocytic leukemia (APL) an revolution in therapy of this disease has been made. The rate of molecular complete remissions (CR) have been doubled compared to conventional chemotherapy with anthracyclines ranging from 90% to 95%. Consolidation therapy is required in order to redu...
By Ivan Petković, Ivica Pejčić, Svetislav Vrbić
Thelazia Callipaeda and Eye Infections
Eye infections can be caused by metazoans - helminths and for long this parasitosis was believed to spread only in tropical regions of the world. Lately, mostly subconjunctival infections of adults or immature forms of D. repens, which is nematoda-filaria of canids, have been described and the man is just an accidental host. The genus Thelazia (Spi...
By Suzana Otašević, Marija Trenkić Božinović, Aleksandar Tasić, Aleksandar Petrović
Risk Factors for Early Postoperative Complications after Surgery for Crohn's Disease
The aim of this study was to show the influence of various risk factors on early postoperative complications following surgery for Crohn’s disease (CD). In this review, an online internet database was searched, and also systematic review of the literature was performed. Three different studies from different countries were analyzed and compar...
By Vladimir Joksimović, Aleksandar Karagjozov, Gjorgi Jota, Ilija Milev, Radomir Gelevski
Bagged Aronia Melanocarpa Tea: Phenolic Profileand Antioxidant Activity
While there is a large number of scientific papers reporting chemical composition and biological activities of Aronia melanocarpa, there is a lack information regarding the commercially available bagged tea. In order to supply new information on the antioxidant activity of the Aronia melanocarpa tea infusions, the aim of this study was to evaluate ...
By Jovana Veljković, Jelena Brcanović, Aleksandra Pavlović, Snežana Mitić, Biljana Kaličanin, Milan Mitić
Epidemiological characteristics of carriers of antibody against hepatitis C virus in the population of Nišava district
The aim of the paper was to determine the disease trends and characteristics of anti-HCV antibody carrier status for the purpose of better prevention and disease control. The materials used were annual reports, reports of diseases and deaths from infectious diseases, and epidemiological surveys of the Public Health Institute Niš in the perio...
By Marina Kostić, Biljana Kocić, Lidija Popović Dragonjić
Bioavailability of heavy metals in the soil from different locations of medicinal herbs
Medicinal herbs and their mixtures, which are widely used for prevention and treatment of some disease, can also present health risks due to the presence of toxic metals such as Pb and Cd. The application of different agrotechnical practices during plant growing season, as well as the process of circulation of substances in nature, may be the cause...
By Biljana Kaličanin, Dragan Velimirović, Ivana Arsić, Sofija Đorđević
Medical Studies in English: Shared Learning
In recent years, medical studies in English have been organized at the Niš Faculty of Medicine. Thus, modern teaching approaches are required. It has been shown that there are many similarities between the two fields - English and medicine. As a result, it is believed that the methods and strategies used in teaching medical English language ...
By Zorica Antić, Nataša Milosavljević
Cancer of Unknown Primary Site Syndrome‐CUP Syndrome - Diagnostic and Therapeutical Dillemas
Metastatic carcinomas of unknown primary origin (cancer of unknown primary-CUP) represent 3-5% of all cancers. This term includes all patients presented with metastatic disease in whom the primary site could not have been identified. Despite the use of modern and comprehensive diagnostic techniques and procedures, there is no improvement in efficac...
By Ivica Pejčić, Svetislav Vrbić, Mirjana Todorović, Ivan Petković, Mirjana Balić, Ana Stanković
Oxidative Stress, Skin Aging and Antioxidant Therapy
Skin aging is a dynamic process that occurs due to chronological and photo-aging caused by the influence of external factors, especially ultraviolet-UV radiation. Cumulative oxidative stress, formation of free radicals and their adverse effects on biological systems in the skin cells is a common mechanism of both skin aging processes. The formed re...
By Dragana Stojiljković, Dušica Pavlović, Ivana Arsić
Extensive Bone Marrow Involvement in Hodgkin Lymphoma Patient
Bone marrow involvement is rare in patients with Hodgkin lymphoma (HL). Its incidence varies with respect to risk factors from 4% to 14%. Low risk patients do not need trephine biopsy according to some research. In the era of positron emission tomography/computed tomography (PET/CT) staging prior to therapy, the role of trephine biopsy as a part of...
By Ivan Petković, Miljan Krstić, Slavica Stojnev, Ivica Pejčić, Svetislav Vrbić