The study of features of pharmacodynamics of a new analgesic is an important and urgent task of modern pharmacology. These data allow us to clarify the nosology for application of an analgesic and to create a theoretical background to optimize its use. An effect mediated by the transient receptor potential cation channel, subfamily V, member 1 (TRP...

By Oleh Yadlovskyi, Tatiana Bukhtiarova, Lyudmila Bobkova, Irina Tatianshenko, Igor Monchak, Andrew Khayrulin

Emergency hormonal contraception is used to prevent unintended pregnancy postcoitally. The mechanism of action of the most frequently used hormonal preparations for emergency contraception, levonorgestrel (LNG) and ulipristal acetate (UPA), is still not fully known, but clinical trials indicate that they act by inhibiting or delaying ovulation. LNG...

By Jelena Milosavljević, Katarina Ilić, Dušanka Krajnović

Osteoporosis is a chronic disease with increasing incidence that predominantly occurs in female population. There are evidences that bisphosphonates, selective estrogen receptor modulators, denosumab, teriparatide and strontium renalate, prevent vertebral fractures while alendronate, risedronate, zoledronic acid, denosumab and strontium renalate pr...

By Ivana Tadić, Ljiljana Tasić, Nada Vujašinović Stupar, Katarina Ilić, Dejan Stevanović

Symptoms of bladder dysfunction are significant public health problem due to their prevalence, morbidity and treatment costs. Most stem from bladder control problem which is governed by the brain, yet we know little about CNS and bladder. Advances in brain imaging technology have brought new insight in how brain works in different bladder diseases ...

By Staša Tadić

Teratomas constitute a group of nongerminomatous germ cell tumors that are composed of an admixture of different tissue types representative of ectoderm, endoderm and mesoderm. Intracranial teratomas are rare, comprising approximately 0.5% of all intracranial tumors. They preferentially involve the midline structures, and occur primarily in childre...

By Irena Dimov, Desanka Tasić, Ivana Stojanović, Simonida Stojanović, Nebojša Stojanović, Ivan Stefanović, Dragan Dimov

Chronic rhinosinusitis is a chronic inflammation of the nasal and paranasal cavities. However, the main pathophysiology of these chronic conditions is poorly described and seems to be multifactorial. In the present study, we reviewed the computed tomography (CT) scans of patients with chronic rhinosinusitis to identify a probable association betwee...

By Seyyed Abdollah Madani, Seyyed Abbas Hashemi, Amir Hosein Kianejad, Saman Heidari

The aim of the research was to quantify the connective tissue and blood vessels in the aging human pituitary, using the morphometric methods. The material contained 29 pituitary tissues from cadavers of both sexes (14 females and 15 males), aged 33-95 years. The pituitary tissue was processed by standard histological procedure and stained by Mallor...

By Miljana Pavlović, Ivan Jovanović, Snežana Pavlović, Vesna Stojanović, Vladimir Živković, Mirjana Bakić, Braca Kundalić, Vladimir Antić

Clindamycin is an antibiotic effective against Gram-positive aerobes and both Gramnegative and Gram-positive anaerobic pathogens. Clindamycin (its phosphate ester) was used as a model drug for our study in order to check the efficacy of the developed vaginal gel formulations. The aim of this study was to develop an analytical method suitable for th...

By Milica Stanković, Vesna Savić, Valentina Marinković

Nutrition plays a very important role in every physical fitness program. Despite many advances in nutritional knowledge and dietary practices, sports nutrition-associated issues are still a challenge. The aim of this study was to determine and compare nutritional knowledge and behavior among the youth practicing sports situated in two different Eur...

By Gabriele Trabucco, Maja Nikoić, Bojana Vuković Mirković

In this study we investigated the effects of four emollients (cetearyl octanoate, decyl oleate, C12-15 alkyl benzoate and olive oil) incorporated at a concentration of 10% on the structural properties of the cosmetic oil/water (o/w) creams (creams K1-K4, respectively) as well as the in vivo effects of those creams on pH and hydration level of the h...

By Dragana Stojiljković, Ivana Arsic, Marija Tasić Kostov, Zoran Jovanović, Vanja Tadić, Sofija Đorđević