Mechanism of Action, Efficacy and Safety of Emergency Hormonal Contraception (levonorgestrel and ulipristal acetate) and Attitudes of Pharmacists
Emergency hormonal contraception is used to prevent unintended pregnancy postcoitally. The mechanism of action of the most frequently used hormonal preparations for emergency contraception, levonorgestrel (LNG) and ulipristal acetate (UPA), is still not fully known, but clinical trials indicate that they act by inhibiting or delaying ovulation. LNG...
By Jelena Milosavljević, Katarina Ilić, Dušanka Krajnović
New drugs for osteoporosis therapy: a review of the clinical trials phase 2 and 3
Osteoporosis is a chronic disease with increasing incidence that predominantly occurs in female population. There are evidences that bisphosphonates, selective estrogen receptor modulators, denosumab, teriparatide and strontium renalate, prevent vertebral fractures while alendronate, risedronate, zoledronic acid, denosumab and strontium renalate pr...
By Ivana Tadić, Ljiljana Tasić, Nada Vujašinović Stupar, Katarina Ilić, Dejan Stevanović
CNS and bladder (short review for clinicians)
Symptoms of bladder dysfunction are significant public health problem due to their prevalence, morbidity and treatment costs. Most stem from bladder control problem which is governed by the brain, yet we know little about CNS and bladder. Advances in brain imaging technology have brought new insight in how brain works in different bladder diseases ...
By Staša Tadić
Mature Intracranial Teratoma
Teratomas constitute a group of nongerminomatous germ cell tumors that are composed of an admixture of different tissue types representative of ectoderm, endoderm and mesoderm. Intracranial teratomas are rare, comprising approximately 0.5% of all intracranial tumors. They preferentially involve the midline structures, and occur primarily in childre...
By Irena Dimov, Desanka Tasić, Ivana Stojanović, Simonida Stojanović, Nebojša Stojanović, Ivan Stefanović, Dragan Dimov
Association Between Anatomical Variations of the Sinonasal Region and Chronic Rhino-Sinusitis: A Prospective Case Series Study
Chronic rhinosinusitis is a chronic inflammation of the nasal and paranasal cavities. However, the main pathophysiology of these chronic conditions is poorly described and seems to be multifactorial. In the present study, we reviewed the computed tomography (CT) scans of patients with chronic rhinosinusitis to identify a probable association betwee...
By Seyyed Abdollah Madani, Seyyed Abbas Hashemi, Amir Hosein Kianejad, Saman Heidari
Morphometric Study of Connective Tissue in the Human Pituitary during Aging Process
The aim of the research was to quantify the connective tissue and blood vessels in the aging human pituitary, using the morphometric methods. The material contained 29 pituitary tissues from cadavers of both sexes (14 females and 15 males), aged 33-95 years. The pituitary tissue was processed by standard histological procedure and stained by Mallor...
By Miljana Pavlović, Ivan Jovanović, Snežana Pavlović, Vesna Stojanović, Vladimir Živković, Mirjana Bakić, Braca Kundalić, Vladimir Antić
Determination of Clindamycin Phosphate in Different Vaginal Gel Formulations by Reverse Phase High Performance Liquid Chromatography
Clindamycin is an antibiotic effective against Gram-positive aerobes and both Gramnegative and Gram-positive anaerobic pathogens. Clindamycin (its phosphate ester) was used as a model drug for our study in order to check the efficacy of the developed vaginal gel formulations. The aim of this study was to develop an analytical method suitable for th...
By Milica Stanković, Vesna Savić, Valentina Marinković
Medication Adherence in Outpatients with Arterial Hypertension
The degree of patient cooperation plays a key role in the success of antihypertensive drug therapy. Non-adherence is the major health and economic problem in the treatment of arterial hypertension (HTA). The aim of the study was to evaluate the degree of adherence in hypertensive patients and to study risk factors affecting adherence and the effect...
By Jelena Lalić, Radmila Veličković Radovanović, Branka Mitić, Valentina Nikolić, Ana Spasić, Goran Koraćević
Nutritional Knowledge and Behavior Among Students Practicing Sports: Comparison Between Two Countries
Nutrition plays a very important role in every physical fitness program. Despite many advances in nutritional knowledge and dietary practices, sports nutrition-associated issues are still a challenge. The aim of this study was to determine and compare nutritional knowledge and behavior among the youth practicing sports situated in two different Eur...
By Gabriele Trabucco, Maja Nikoić, Bojana Vuković Mirković
Investigation of the Effects of Different Emollients on the Structure and Skin Moisturizing Potential of the Cosmetic Creams
In this study we investigated the effects of four emollients (cetearyl octanoate, decyl oleate, C12-15 alkyl benzoate and olive oil) incorporated at a concentration of 10% on the structural properties of the cosmetic oil/water (o/w) creams (creams K1-K4, respectively) as well as the in vivo effects of those creams on pH and hydration level of the h...
By Dragana Stojiljković, Ivana Arsic, Marija Tasić Kostov, Zoran Jovanović, Vanja Tadić, Sofija Đorđević