The sequence of precursor lesions for squamous cell carcinoma may be hyperplasia-metaplasia-dysplasia-carcinoma in situ. The aim of this study was to perform a karyometric analysis of squamous metaplasia, moderate dysplasia and squamous cell lung carcinoma. Bronchoscopic biopsies of normal mucosa in chronic bronchitis patients (n = 10), squamous me...

By Žaklina Mijović, Zoran Pešić, Nikola Živković, Tijana Denčić, Ana Ristić Petrović, Slavica Stojnev

Uvae ursi folium (Arctostaphylos uva ursi, Ericaceae) is the best known and most widely used herbal urinary antiseptic. In traditional medicine, other Ericaceae species are also used for the treatment of urinary tract infections. The present study investigates antimicrobial activity of five species of Ericaceae family native to the Balkan Peninsula...

By Dragana Pavlović, Branislava Lakušić, Dušanka Kitić, Milica Milutinović, Milica Kostić, Bojana Miladinović, Nada Kovačević

Ultrastructure of adhesive bond is a significant indicator of the efficiency of the bond between material and dental tissue. Bonding between composite and hard dental tissue is also most commonly assessed by measuring bonding strength or by absence of marginal gap along restoration interface. The aim of this investigation was to estimate ultrastruc...

By Stefan Dačić, Aleksandar Mitić, Jelena Popović, Dragica Simonović Dačić, Marko Igić

The aim of our study was to analyze the changes of connective tissue sheaths of epi-, peri- and endoneurium of sural nerve during aging. The study was conducted on sural nerve samples of 10 cases aged 9-80 years. The specimens were embedded in paraffin using standard procedures, after which 5-μm-thick cross-sections of nerve trunks were made and...

By Braca Kundalić, Slađana Ugrenović, Ivan Jovanović, Natalija Stefanović, Vladimir Petrović, Jasen Kundalić, Miljana Pavlović, Vladimir Antić

In search for new and promising coumarin compounds as HIV-1 integrase inhibitors, chemoinformatic methods like quantitative structure-activity relationships (QSAR) modeling and molecular docking have an important role since they can predict desired activity and propose molecule binding to enzyme. The aim of this study was building of QSAR models fo...

By Jovana Veselinović, Aleksandar Veselinović, Andrey Toropov, Alla Toropova, Ivana Damnjanović, Goran Nikolić

The aim of the paper was to show the diagnostic and therapeutic approaches to a patient suffering from osteomalacia, as well as differential diagnosis with osteoporosis. Osteomalacia (OM) is a metabolic disease of bones which appears as a result of defective mineralization of newly formed bone matrix in adults. Diagnosis of disease may represent a ...

By Nela Živković, Sonja Stojanović

Isoform 2 of calsequestrin (CASQ2) is the main calcium-binding protein of sarcoplasmic reticulum (SR), expressed both in cardiac and in skeletal muscles. CASQ2 acts as an SR calcium (Ca2+) sensor and regulates SR Ca2+ release via interactions with triadin, junctin, and the ryanodine receptor. Various mutations of the csq2 gene lead to altered Ca2+ ...

By Rigers Bakiu

Pain is a worldwide health disorder causing depression and decrease in daily activities, as well as cognitive, memory and attention impairments. In this regard, mucosal contact headache is a second type of headache disorder in the International Classification of Headache Disorders. Some studies have reported that contact points may work as triggers...

By Seyyed Abdollah Madani, Seyyed Abbas Hashemi, Seyyed Amirhosein Morshedzadeh

During inflammation, lymphangiogenesis takes place to enhance the transport of filtered fluid, proteins, and immune cells. Dental pulp tissue is frequently exposed to inflammatory insults, but the lymphatic system of the pulp and its responses to injury have not been investigated in detail using specific lymphatic markers. The aim of this study was...

By Dragica Dačić Simonović, Ljubinka Veličković Janković, Stefan Veličković, Ana Ristić Petrović, Stefan Veličković, Aleksandra Petrović, Martina Rakonjac

This paper describes the utility of flexible bronchoscopy in a sick child diagnosed with dermatomyositis, celiac disease. Mucus plug is a common medical cause of lung atelectasis. Due to deteriorated respiratory condition, the child was highly febrile, cyanotic, liver 6-7 cm, palpable under the right rib arch. We described a child with dermatomyosi...

By Amina Selimović, Milan Rančić, Ermina Mujičić, Senka Mesihović Dinarević, Aida Hasanović, Siniša Ristić, Zoran Svetozarević