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By Zoran Damnjanović, Milan Jovanović, Predrag Đorđević, Nenad Ilić, Irena Janković, Igor Smiljković, Nikola Đorđević, Dragutin Grozdanović

SUMMARY The high incidence of premalignant lesions of the cervix in our country and worldwide was the primary aim for conducting this study so as to establish whether HPV16, smoking and coitarche (first intercourse) are significant factors in the developmental stages of cervical dysplasia in the case of which the conization is a surgical treat...

By Goran Dimitrov, Elena Džikova, Gligor Dimitrov, Gjorgji Babushku, Vesna Antovska

SUMMARY Hair loss is not a common feature of secondary syphilis. There are two types of syphilitic alopecia: “symptomatic” type where hair loss is associated with other symptoms of secondary syphilis, and “essential” alopecia that is either patchy (“moth-eaten” type), diffuse pattern with a generalized thinning of the scalp hair, or a combinat...

By Milan Bjekić

SUMMARY In the recent years the exposure to environmental tobacco smoke (ETS) has been an important public health hazard, especially in Serbia, a country with too many smokers. A common component of tobacco smoke is particulate matter less than 10μm in aerodynamic diameter (PM10), which is considered to be the most dangerous air pollutant for ...

By Maja Nikolić, Aleksandra Stanković, Ivana Mladenović Ćirić

Spermine Oxidation Products Induce Mitochondrial Alterations on Tumor CellsCytotoxic products of polyamines generatedin situby an enzyme-catalyzed reaction may be useful as a new avenue in combating cancer. This study demonstrates that multidrug resistant (MDR) cancer cells (colon adenocarcinoma and melanoma) are significantly more sensitive than t...

By Enzo Agostinelli

SUMMARY Cervical tuberculosis is a rare disease with a high complication rate. Tuberculosis of the cervical spine is reported in about 6-9% of all cases of spinal tuberculosis. Early diagnosis and treatment of spinal tuberculosis is essential in order to prevent neural deficit. Management strategies for spinal tuberculosis range from ambulator...

By Saša Milenković, Jordan Saveski, Ilir Hasani, Neda Trajkovska, Venko Filipče

01.12.2011. Research paper
Polyamines and carcinogenesis

SUMMARY The naturally occurring polyamines, spermine, spermidine and the diamine putrescine are widespread in nature. They have been implicated in growth and differentiation processes. In 1967, we reported that cancer cells are rich in polyamines. Subsequently, it has been shown that polyamines are released from cancer cells and may be detecte...

By Uriel Bachrach

SUMMARY Progress in medical care witnessed nowadays has resulted in the increase of the survival rate of infants affected or at risk of some psychomotor development disorders. High psychomotor risk may be associated with perinatal risk factors, preterm delivery as well as hereditary diseases. Each child with the so-called positive perinatal fa...

By Marta Szmaj

SUMMARY The paranasal sinus mucocele is an epithelized cystic lesion containing fluid and is characterized by non-neoplastic expansion of the paranasal sinus due to its capacity to erode the overlying bone. Etiology of these lesions is still under debate. In this report, we described a case of a patient with frontal recess mucocele, associated ...

By Aleksandar Perić, Milan Erdoglija, Nenad Mladenović, Biserka Vukomanović Đurđević