SUMMARY The naturally occurring polyamines, spermine, spermidine and the diamine putrescine are widespread in nature. They have been implicated in growth and differentiation processes. In 1967, we reported that cancer cells are rich in polyamines. Subsequently, it has been shown that polyamines are released from cancer cells and may be detecte...

By Uriel Bachrach

SUMMARY Progress in medical care witnessed nowadays has resulted in the increase of the survival rate of infants affected or at risk of some psychomotor development disorders. High psychomotor risk may be associated with perinatal risk factors, preterm delivery as well as hereditary diseases. Each child with the so-called positive perinatal fa...

By Marta Szmaj

SUMMARY The high incidence of premalignant lesions of the cervix in our country and worldwide was the primary aim for conducting this study so as to establish whether HPV16, smoking and coitarche (first intercourse) are significant factors in the developmental stages of cervical dysplasia in the case of which the conization is a surgical treat...

By Goran Dimitrov, Elena Džikova, Gligor Dimitrov, Gjorgji Babushku, Vesna Antovska

SUMMARY Hair loss is not a common feature of secondary syphilis. There are two types of syphilitic alopecia: “symptomatic” type where hair loss is associated with other symptoms of secondary syphilis, and “essential” alopecia that is either patchy (“moth-eaten” type), diffuse pattern with a generalized thinning of the scalp hair, or a combinat...

By Milan Bjekić

SUMMARY In the recent years the exposure to environmental tobacco smoke (ETS) has been an important public health hazard, especially in Serbia, a country with too many smokers. A common component of tobacco smoke is particulate matter less than 10μm in aerodynamic diameter (PM10), which is considered to be the most dangerous air pollutant for ...

By Maja Nikolić, Aleksandra Stanković, Ivana Mladenović Ćirić

Stercoral peritonitis (SP) caused by perforation of the colon due to colorectal carcinoma (CRC) represents one of the most difficult types of peritoneal inflammation with complex clinical presentation. The aim of the study was to establish the frequency of CRC as a cause of stercoral peritonitis, type of treatment, postoperative complicatins, lengt...

By Ivana Đorđević, Goran Stanojević, Dragoslav Miljković, Aleksandar Bogićević, Hadži-Bojan Marjanović

High prevalence of hypertension along with its serious complications in the organs have made this disease an important health problem worldwide. The lack of symptoms is the most important sign of hypertension and the prevalent remedies have not been effective in controlling the disease yet. Meanwhile, monitoring blood pressure at home and at workpl...

By Ivana Ilić, Jovica Jovanović, Mirjana Aranđelović

It is not enough just to do mammography, but perform a quality one. American Association of Radiologists (American College of Radiology - ACR) introduced a unique and a standard terminology in radiological diagnosis of breast disease calling it the Breast Imaging Reporting and Data System or abbreviated BIRADS.  The aim of the paper is to pres...

By Rade Babić

Palpable lymphadenopathy presents a serious diagnostic and therapeutic problem in primary care. The patients are often referred to a specialist with delay and even more often they are referred to unneeded diagnostic and therapeutic procedures. Empiric treatment with antibiotics and corticosteroids and extraction of often healthy teeth commonly lead...

By Stefan Lukić, Goran Marjanović, Jovana Živanović

In many physiological processes, peptides play a critical role as neurotrans mitters, hormones, antibiotics, etc. They have research importance in fields such as immunology, pharmacology, neuroscience and cell biology. There are many approaches for immunotherapies: some of them use the peptides as important components of chimeric molecules for immu...

By Nikolina Mihaylova, Andrey Tchorbanov