Ketorolac is a potent non-steroidal anti-inflammatory drug (NSAID) that can inhibit cyclooxygenase activity and prostaglandin synthesis, thereby reducing pain and inflammation. The aim of this study was to investigate the hepatorenal toxicity of ketorolac administration in adult male rats. Twenty-four adult male Wistar rats were randomly assigned t...

By Fatemeh Rashidi, Amir Noyani, Salma Omidi, Touraj Assadi

Artificial intelligence (AI) offers transformative potential in healthcare management by enhancing predictive analytics, optimizing resource allocation, and supporting clinical decision-making. This study aims to examine the applications of AI in Serbian healthcare institutions, focusing on improving operational efficiency and patient outcomes. The...

By Milić Kimi, Šćepan Sinanović, Tatjana Kilibarda, Saša Bubanj, Novica Bojanić, Tanja Prodović

Splenic abscess is a very rare extra-intestinal complication of Salmonella infection in the post-antibiotic era with the incidence between 0.14% and 2%. It usually follows bacteremia due to varied etiologies such as trauma, infective endocarditis, intravenous drug abuse, immunodeficiency status (AIDS, diabetes mellitus). An 82-year-old woman presen...

By Milan Pantelić, Tamara Vučinić, Milica Stanucević, Miloš Dujović, Maša Pantelić

Many markers are used to evaluate the prognosis in patients with acute myocardial infarction (AMI). Researches are focused on available markers with high sensitivity and specificity. The aim of our study was to evaluate the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and its superiority compared with other prognostic ma...

By Rada Vučić, Vladimir Ignjatović, Olivera Andrejić, Katarina Čupić, Miodrag Srećković, Filipović Vučković, Marija Sekulić, Milan Dobrić, Jelena Rakočević

Glioblastomas (GBMs) are among the most vascularized human tumors and the presence of microvascular proliferation is one of the diagnostic hallmarks of these malignancies. The aim of the present study was to investigate the extent of vascularization and its relation to proliferative activity and the p53 status in GBMs. Tissue samples from 100 selec...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Dragan Dimov

Drug-induced esophageal injuries are rare in clinical practice. Doxycycline is the most common antibiotic that can damage the esophagus. We present a 26-year-old woman who visited a gastroenterologist because of difficulty swallowing and pain during swallowing. After laparoscopic treatment of endometriosis, the gynecologist prescribed her doxycycli...

By Stojanov Benedeto, Gordana Petrović, Andrija Rančić, Jovičić Milentijević, Radmila Veličković, Nebojša Ignjatović, Dragan Stojanov

Parkinson's disease (PD) is a chronic, neurodegenerative disorder that in certain stages can present a series of acute symptoms and signs, the development of which lasts several hours or days. Emergencies in PD can be a direct consequence of the pathophysiology of the disease or a secondary consequence of the administration of antiparkinsonian drug...

By Jelena Stamenović, Vuk Milošević, Vanja Đurić

Restoring the morphological and functional integrity of damaged or lost teeth and replacing them with suitable materials remains a significant challenge in modern dentistry. A continuous development of new restorative materials aims to improve mechanical properties, aesthetic outcomes, and longevity of dental restorations, while minimizing adverse ...

By Ana Pejčić, Milena Kostić, Ivana Stankovic, Radmila Obradovic, Marija Bradic-Vasic, Marija Đorđević, Marko Igic, Nikola Gligorijević

Pre-eclampsia is a major cause of perinatal mortality. Glutamate plays a critical function in the promotion of a healthy pregnancy. Therefore, the aim of this study was to determine the extent of the correlation between pre-eclampsia and 4-hydroxyglutamate acid. This is a case-control study that was conducted on a sample of 100 pregnant women in th...

By Noor Fawzi, Sheikh Al

Cystic changes of the spleen are one of the rare clinical entities in the pediatric population. The paper presents a partial splenectomy in children performed by open approach as a safe surgical treatment of giant epithelial splenic cysts. Two cases of giant epithelial cysts of the spleen in children are presented. Medical documents and data referr...

By Maja Zečević, Zoran Marjanović, Dragoljub Živanović, Goran Janković, Nikola Živković, Živojin Spasić, Strahinja Konstantinović