Artificial intelligence (AI) is reshaping personalized medicine by enabling earlier diagnosis, tailored therapies, and faster drug discovery. The aim of the paper was to synthesize current evidence on AI applications in precision healthcare and quantify their impact on diagnostics, therapeutic decision-making, and discovery. We conducted a systemat...

By Marko Kimi Milić, Šćepan Sinanović, Tatjana Kilibarda, Saša Bubanj

When making complete dentures, both functional and aesthetic criteria need to be met so that the patient can accept the prosthetic restoration more easily and be satisfied with it. The aim of the research was to determine smile parameters as anthropological criteria for the selection of teeth when making complete dentures. The study included 91 den...

By Milena Kostić, Marko Igic, Marija Đorđević, Ermin Đerlek, Ana Pejcic, Nikola Gligorijević, Ivana Stankovic, Nadica S. Đorđević, Marija Andjelkovic Apostolovic

Burns represent one of the leading causes of morbidity and mortality in children. Aim. Aim of this review is to gain better understand of the pathophysiological changes and assessment of the severity of burn injuries in different ages of pediatric patients, which may help in early implementation of appropriate therapeutic procedures and improvement...

By Vesna Marjanović

Retinitis pigmentosa (RP) is a diverse group of inherited retinal diseases characterized by the gradual degeneration of rod and cone photoreceptors in the retina. RP is primarily inherited, with numerous genetic mutations implicated in its pathogenesis. The aim of this study was to summarize the findings of studies related to genes implicated in re...

By Olivia Narváez, Zerón Mendieta, Orlando Torres, Magally Escobar, Martha Trujillo-Güiza

Esophagogastric varices develop in 50-60% of patients with liver cirrhosis, and 30% of them have one episode of variceal hemorrhage within two years of variceal diagnosis. The aim of the paper was to present the latest attitudes in the treatment of esophagogastric varices. Literature review. Prevention of first bleeding from esophageal varices (EV)...

By Ivan Grgov, Daniela Benedeto-Stojanov, Biljana Radovanović-Dinić, Milica Grgov, Saša Grgov, Tomislav Tasić

Although we could not find the registered cases of leptospirosis co-occurring with lymphogranulomatosis, it is important to note that both diseases can affect the immune system. Therefore, the reported case is unique and will be interesting and useful for the physicians of various specialties. We report a case of icterohemorrhagic form of leptospir...

By Borys Fylenko, Ivan Starchenko, Nataliia Roiko, Iryna Kornilova, Anatolii Romanyuk, Mykola Lyndin

Seat belt syndrome (SBS) is a new pattern of injuries in road traffic accidents (RTAs). It refers to injuries caused by the interaction of the human body and the safety belt and consists of a wide spectrum of injuries (musculoskeletal and visceral). In this paper, we present a case of a front-seat passenger with polytrauma sustained in an RTA, who,...

By Slađana Anđelić, Eleftheria Papadopoulou, Tanja Nikolić, Goran Čolaković, Milena Popović

Immune checkpoint inhibitors (ICIs) immensely improved outcomes in melanoma patients. Vitiligo-like depigmentation (VLD) is a well-documented adverse event of ICIs which is well tolerated and often associated with prolonged response to treatment. The aim of this study was to assess the effect of VLD occurrence on survival in melanoma patients treat...

By Aleksandar Popović, Ana Stojković, Ana Cvetanović, Andrija Jović, Milica Radić, Irena Conić, Ivan Petković

Multiple myeloma is the second most common hematological malignancy in which pathological plasma cells secrete monoclonal proteins, ultimately leading to end-organ damage. Albumin, β2-microglobulin, and LDH are considered highly relevant biomarkers for the diagnosis and prognosis of this disease. There are different types of treatment availabl...

By Ina Konstantinović, Irena Ćojbašić, Miodrag Vučić

People with circadian rhythm disturbances are at an elevated risk of mental disorders, and conversely, those with mental disorders are more susceptible to the circadian disruption. A steady circadian cycle of sleep and wakefulness that is phase-shifted relative to the prior local solar time may be characterized by a short endogenous circadian perio...

By Dmytro Boiko, Oksana Mats, Anastasiia Shkodina, Andrii Skrypnikov