×
Home
Archive Submission Guidelines
News Contact
Original article
Crossmark

Investigation of efficacy of anti-aging liposomal intimate gel: An in vivo long-term study

By
Ivana Nešić ,
Ivana Nešić
Vesna Savić ,
Vesna Savić
Ana Kolarević
Ana Kolarević

Abstract

Liposomes have been used as universal carriers for decades, encapsulating many compounds with different cosmetic effects in order to achieve the quality, safety and efficacy of functional cosmetic products. In the present study, the efficacy of the application of the commercial liposome gel (SOPHY Anti-Aging Liposomal Intimate Gel), containing L-arginine, white curcuma extract, hyaluronic acid, lactic acid and vitamin E (previously shown to have various positive effects on the skin) as encapsulated cosmetic active ingredients, was examined in vivo on healthy volunteers. During a long-term 28-day study, biophysical skin parameters (skin humidity, TEWL, EI and pH) were monitored. As a result, an increase in skin hydration, decrease in TEWL, and a slight decrease in EI and skin pH were observed. Thus, the examined cosmetic product has shown a positive effect on skin hydration, contributing to the renewal of skin barrier, also having the anti-irritating effects.

References

1.
Rahimpour Y, Hamishehkar H. Liposomes in cosmeceutics. Expert Opinion on Drug Delivery. 2012;9(4):443–55.
2.
Bozzuto G, Molinari A. Liposomes as nanomedical devices. International Journal of Nanomedicine. :975.
3.
Darlenski R, Sassning S, Tsankov N, Fluhr JW. Non-invasive in vivo methods for investigation of the skin barrier physical properties. European Journal of Pharmaceutics and Biopharmaceutics. 2009;72(2):295–303.
4.
Piérard GE, Paquet P, Preudhomme L, Noël F, Quatresooz P. Skin Bioengineering. Kanerva’s Occupational Dermatology. 2012. p. 991–1001.
5.
Vuleta G, Savić S. Opravdanost primene vitamina i minerala u kozmetičkim proizvodima. Arh Farm. 2009;59(2–3):212–25.

Citation

Article metrics

Google scholar: See link

Citations

Crossref Logo

6

Crossref Logo

Zarith Asyikin Abdul Aziz, Wong Lee Peng, Hasmida Mohd Nasir, Nurul Asmak, Siti Hamidah Mohd Setapar, Akil Ahmad

(2022)

Nanotechnology for the Preparation of Cosmetics Using Plant-Based Extracts

, ()

10.1016/B978-0-12-822967-5.00015-1

Crossref Logo

Cheng Cheng, Enzo Terreno

(2024)

Development of a versatile optical pH sensor array for discrimination of anti-aging face creams

Talanta, 278()

10.1016/j.talanta.2024.126447

Crossref Logo

Bhavana B. Bhat, Prateeksha Prakash Kamath, Swarnabh Chatterjee, Rishav Bhattacherjee, Usha Y. Nayak

(2022)

Recent Updates on Nanocosmeceutical Skin Care and Anti-Aging Products

Current Pharmaceutical Design, 28(15)

10.2174/1381612828666220321142140

Crossref Logo

Zarith Asyikin Abdul Aziz, Siti Hamidah Mohd Setapar

(2022)

Nanotechnology for the Preparation of Cosmetics Using Plant-Based Extracts

, ()

10.1016/B978-0-12-822967-5.00009-6

Crossref Logo

Yasmin R. Maghraby, Ahmed H. Ibrahim, Rehan M. El-Shabasy, Hassan Mohamed El-Said Azzazy

(2024)

Overview of Nanocosmetics with Emphasis on those Incorporating Natural Extracts

ACS Omega, ()

10.1021/acsomega.4c00062

Crossref Logo

Ioana Lavinia Dejeu, Laura Grațiela Vicaș, Eleonora Marian, Mariana Ganea, Olimpia Daniela Frenț, Paula Bianca Maghiar, Flaviu Ionut Bodea, George Emanuiel Dejeu

(2024)

Innovative Approaches to Enhancing the Biomedical Properties of Liposomes

Pharmaceutics, 16(12)

10.3390/pharmaceutics16121525

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.