Introduction/Aim. This study aimed to determine the effect of the self-efficacy enhancement program on medication adherence and self-efficacy in patients with the acute coronary syndrome. Methods. The parallel randomized clinical trial study was conducted on 86 patients with the acute coronary syndrome in Shahroud, Iran, by using a convenience sampling method. Data collection tools included a demographic questionnaire and a self-efficacy scale for appropriate medication. The self-efficacy enhancement program group received the self-efficacy program in five sessions of 30 to 45 minutes for 40 days, and the control group received routine support. The data were analyzed using descriptive and inferential statistics. The level of significance was considered at 0.05. Results. After the intervention, a greater improvement in self-efficacy score (p < 0.001) and higher medication adherence score (p < 0.001) were observed in the self-efficacy enhancement program group than the control group. Conclusion. Considering the results of the present study, the self-efficacy enhancement program improves self-efficacy and medication adherence in acute coronary syndrome patients. Therefore, it is recommended to apply this intervention as an effective method.
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