The internal carotid artery (ICA) is a paired artery that primarily supplies the anterior two-thirds of the brain, the pituitary gland, the eye structures, and some other cranial structures. The ICA variations or abnormalities have been more or less described; especially, bilateral ICA hypoplasia (ICAH) was a very rare description that inspired aut...

By Ljiljana Vasović, Ana Mrkaić, Miracle Wangsuwana, Dimitrije Đorđević, Milena Trandafilović

Epidermal growth factor receptor (EGFR) is one of the key tumor markers of non-small cell lung cancer (NSCLC) and a guideline for the choice of therapeutic procedures. The research aims to evaluate the methods used in the investigation of EGFR variants in NSCLC cell lines and combined research (NSCLC cell lines and patient samples) in the last deca...

By Jovana Todosijević-Jovanović, Jasmina Obradović

Microencapsulation technology can be used for the protection of Alpha-tocopherol from degradation in unfavorable environments and enhancement of bioavailability and shelf-life of vitamin E. The aim of this study was the synthesis and characterization of alginate microparticles for the oral delivery of a-tocopherol. Four different formulations of Al...

By Milja Živković, Ana Barjaktarević, Marina Tomović, Anđela Uštević

Although COVID-19 is present in a milder form nowadays, systemic disorders caused by the virus lead to multiple organ malfunctions. Skin manifestations are the consequence of the disease itself but also the result of preventative measures taken to avoid the infection. They generally do not require pharmacotherapy except in severe cases. Depending o...

By Marija Tasić-Kostov

The incidence of acute myocardial infarction (AMI) is declining in developed countries due to better prevention and more effective treatment of risk factors, however, the proportion of younger patients with AMI is increasing. The aim of the research was to compare patients under the age of 45 years with acute myocardial infarction at a ten-year int...

By Danijela Đorđević-Radojković, Miodrag Damjanović, Svetlana Apostolović, Jelena Milošević, Dragana Stanojević, Goran Koraćević, Ružica Janković-Tomašević, Tomislav Kostić, Sonja Dakić, Jelena Cvetković, Jovana Šarić

Currently, there is no classification reflecting the severity of complicated intra-abdominal infections (cIAIs). Therefore, we aimed to create one and facilitate the prognostic assessment of cIAIs in clinical practice. This was a single-center study conducted at a University Hospital Stara Zagora including 140 patients with cIAIs. Retrospectively, ...

By Evgeni Dimitrov, Georgi Minkov, Emil Enchev, Yovcho Yovtchev

During the SARS-CoV-2 pandemic, there was a significant number of cases accompanied by thrombosis. The precise pathophysiological mechanism remains unclear. The importance of the fibrinolytic mechanism in maintaining physiological hemostasis led us to explore its potential contribution to COVID-19-induced thromboembolism. This study aimed to identi...

By Igor Spasić, Dejan Dobrijević, Biljana Vučković

Laryngectomy is a surgical procedure for the removal of the larynx, either entirely (total laryngectomy) or partially (partial laryngectomy). Rehabilitation of laryngectomy patients is a complex process that involves physical, psychological, and social aspects. To improve the quality of life of laryngectomy patients, rehabilitation consists of seve...

By Dina Rujević, Mirjana Petrović-Lazić

Seminal fluid analysis (SFA) plays a crucial role in helping infertility clinics diagnose the underlying reason of male infertility. The aim of the study was to investigate seminal fluid patterns of male partners of an infertile couple with apparently fertile female partners. A cross-sectional study was conducted between January 2019 and December 2...

By Harith Mohamed Kamber, Kamal Al-Jawdah, Salam Madhi Shahid, Zaid Al-Atta

Polypharmacy can increase the risk of side effects and cause adverse drug interactions with a significant impact on the course of the basic disease. The aim of the study was to determine the frequency of polypharmacy and examine its impact on the risk of drug-drug interactions in patients with rheumatoid arthritis (RA). The research was conducted i...

By Nikola Krstić, Nikola Stefanović, Milan Petronijević, Ivana Damnjanović