Numerous clinical trials have proven the connection between two glandular organs, in this case, the breast and the thyroid gland. The occurrence of breast cancer (BC) is increased in patients with autoimmune thyroid disease (Hashimoto's thyroiditis and Graves' disease). Patients with Graves' disease have a significantly smaller number of described ...

By Tijana Veljković, Dragana Bubanja, Nataša Zdravković, Željko Todorović, Radiša Vojinović, Mladen Maksić

Epidermal growth factor receptor (EGFR) is one of the key tumor markers of non-small cell lung cancer (NSCLC) and a guideline for the choice of therapeutic procedures. The research aims to evaluate the methods used in the investigation of EGFR variants in NSCLC cell lines and combined research (NSCLC cell lines and patient samples) in the last deca...

By Jovana Todosijević-Jovanović, Jasmina Obradović

Microencapsulation technology can be used for the protection of Alpha-tocopherol from degradation in unfavorable environments and enhancement of bioavailability and shelf-life of vitamin E. The aim of this study was the synthesis and characterization of alginate microparticles for the oral delivery of a-tocopherol. Four different formulations of Al...

By Milja Živković, Ana Barjaktarević, Marina Tomović, Anđela Uštević

Polypharmacy can increase the risk of side effects and cause adverse drug interactions with a significant impact on the course of the basic disease. The aim of the study was to determine the frequency of polypharmacy and examine its impact on the risk of drug-drug interactions in patients with rheumatoid arthritis (RA). The research was conducted i...

By Nikola Krstić, Nikola Stefanović, Milan Petronijević, Ivana Damnjanović

Alexithymia is manifested by limited abilities to identify and express emotions and is a possible risk factor for the onset and treatment of the disease. To determine the dependence of the presence of alexithymia in patients with chronic lung and heart diseases. One hundred respondents aged 35 to 75 participated in the research, 50% of whom were be...

By Marija Lazarević

Congenital hypoplasia of the left atrial appendage (LAA) with stenotic ostium in an abnormal position is an extremely rare entity. We report an exceptional case of hypoplastic LAA with ostial stenosis in an abnormal location in the patient with mitral valve stenosis that was mistaken in the transesophageal echocardiography (TEE) for an intraluminal...

By Feridoun Sabzi, Aghigh Heydari, Mohammad Rouzbahani, Atefeh Asadmobini

Hepatitis A virus is a major cause of acute viral hepatitis worldwide, with approximately 1.5 million cases annually. Clinical manifestations of the hepatitis A virus infection range from asymptomatic to acute liver failure. Cholestatic viral hepatitis A is a rare clinical manifestation characterized by a prolonged course, refractory pruritus, immi...

By Nemanja Đorđević, Predrag Čanović, Dejan Petrović, Nataša Minić, Željko Mijailović

The incidence of liver cancer is increasing globally. Fatty acids in lipid metabolism are associated with cancer risk by maintaining cancer cell membrane structure and transducing cancer signaling, and their increased synthesis promotes tumor growth, angiogenesis, and tumor metastasis. After identification of the ELOVL3 gene involved in fatty acid ...

By Yiyang Chen, Wanbang Zhou, Yiju Gon, Xi Ou

Lentigo maligna (LM) represents an in situ melanoma that develops on chronically photo-damaged skin. Clinical diagnosis of LM is often difficult, even for experienced dermatologists. The aim of the study was to analyze the clinical and dermoscopic features of patients with pathohistologically verified lentigo maligna (LM) and to determine a possibl...

By Danica Tiodorović, Danijela Popović, Slađana Cekić, Milica Radić, Aleksandar Popović, Nataša Vidović, Andrija Jović

The loss of the jaw bone, especially in the area of the alveolar process, can significantly complicate the procedure of prosthetic rehabilitation of prosthetic patients. The reason for the loss of the jaw bones are physiological and pathological processes. Bone replacements are widely used in the reconstruction of bone defects. The optimal characte...

By Marko Igić, Milena Kostić, Ana Pejčić, Nikola Gligorijević, Marija Jovanović, Nenad Stošić