N-[2-(5-methoxy-1h-indole-3-yl)ethyl]acetamide may correct arterial hypertension in people with sleep problems
Sleep disturbance is a frequent complaint of patients suffering from arterial hypertension (AH) for a long time. A hidden and uncontrolled increase in blood pressure (BP) makes the course of physiological processes more difficult, disrupts the regulation of biological rhythms, and increases the risk of cardiovascular complications even with a short...
By Mikhail Osadchuk, Inna Vasilieva, Ekaterina Mironova, Nikolay Korzhenkov, Maxim Trushin
Lemon balm (Melissa officinalis L.) hydrolate poorly influences isolated rat gastric fundus motility
Lemon balm has been used for centuries due to its strong sedative, antimicrobial and spasmolytic effects. Besides different types of extracts and essential oils, hydrolates (by-products obtained during essential oil extraction) are preparations of aromatic medicinal plants with potential pharmacological activity. To estimate Melissa officinalis lea...
By Nikola Stojanović, Sara Mladenović, Bogdan Stojiljković, Aleksandar Marković, Dragana Pavlović, Pavle Ranđelović, Jelena Zvezdanović, Ljiljana Stanojević
Fecal calprotectin: A marker of Crohn's disease activity
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) with periods of remission and exacerbation. Numerous studies have been conducted in order to identify the ideal marker when it comes to the inflammatory bowel diseases. In the literature, fecal calprotectin is mentioned as a marker of inflammation. Elevated levels of calprotectin ca...
By Mladen Maksić, Tijana Veljković, Mirjana Cvetković, Marija Marković, Saša Perić, Olivera Marinković, Nataša Zdravković
The impact of biological therapy on health-related quality of life in patients with psoriasis
Psoriasis is a chronic, relapsing, non-infectious dermatosis, affecting patients' quality of life. There is still insufficient evidence from routine clinical practice on how the biological therapy improves the quality of life of patients with psoriasis. The aim of our study was to examine the effectiveness of biological therapy, regardless of the d...
By Katarina Nikolić, Dragan Jovanović, Lena Stojković
In vitro antimicrobial activity of different Verbascum niveum extracts
Medicinal plants are the main ingredient of numerous medicines and pharmaceutical products, and antimicrobial activity has been demonstrated in a large number of medicinal plant extracts and essential oils. Considering that Verbascum L. species (mullein), officially approved by the European Medicines Agency, show antimicrobial properties, but also ...
By Maja Grigorov, Dragana Pavlović, Snežana Mladenović-Antić, Marija Tasić-Kostov, Dušan Ilić
Chronic granulomatous invasive fungal sinusitis: A review of the literature and report of a case atypical of the Balkan region
Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is an extremely rare form of invasive fungal sinusitis. The disease has a long-lasting and indolent course, so the invasion and destruction in the sinonasal and adjacent regions is progressing slowly. This disease has been reported primarily in Middle East, North Africa, India and Pakist...
By Milica Labus, Jelena Sotirović, Biserka Vukomanović-Đurđević, Aleksandar Perić
Antimicrobial activity evaluation of black currant (Ribes nigrum L.) variety Čačanska crna juice and extract
This study aimed to evaluate and quantify the antimicrobial activity of lyophilized fruit juice (BCLJ) and waste extract (BCLW) obtained from the black currant (Ribes nigrum L.) variety Čačanska crna. The study was conducted using four Gram (+) (Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus, Enterococcus faecalis) and five Gram (-)...
By Milica Trajković, Dušanka Kitić, Tatjana Mihajilov-Krstev, Katarina Šavikin, Milica Ranđelović, Milica Milutinović, Suzana Branković, Nemanja Kitić, Bojana Miladinović
Psychoeducational training for healthcare workers psychoeducational training for reducing the impact of COVID-19 pandemic on healthcare workers
Healthcare workers are increasingly exposed to long-term traumatic events in the context of the COVID-19 pandemic. We conducted a study that included 100 healthcare workers and 50 healthy individuals. We used the Perceived Stress Scale, Hospital Anxiety and Depression Scale, and Global Patient Impression for Improvement in the assessment of the psy...
By Dmytro Boiko, Oksana Mats, Liliia Zhyvotovska, Larysa Herasymenko, Andrii Skrypnikov
The effect of transcranial direct current stimulation (tDCS) on seizure control and epilepsy prevention
Epilepsy is one of the most common neurological diseases. It is an uncontrollable neuronal activity of different parts of the brain leading to convulsion and/or fainting. Although epileptic seizure control and therapeutics have significant advances, 20% -30% of individuals still have uncontrolled seizures. Patients under the medication's control ar...
By Moghadam Zahedi, Rabi Atabaki, Hossein Khaleghzadeh-Ahangar
Pathophysiological and laboratory aspects of hemostatic disorders in patients with COVID-19
Although coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), primarily affects the respiratory system, the possibility of multisystem tissue and organ damage is not excluded. In severe forms of the disease, hematological disorders with the accompanying laboratory derangements often occur. The...
By Jelena Đorđević, Olgica Mihaljević, Marijana Stanojević-Pirković, Ardahanli Isa, Milan Radović, Batrić Babović