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For the first time, we evaluated and presented the socio-demographic characteristics, clinical manifestations and laboratory findings of hospitalized coronavirus disease 2019 (COVID-19) patients from Canton Sarajevo, Bosnia and Herzegovina. This retrospective, single-centre study included 159 RT-PCR verified COVID-19 patients (92 mild/moderate; 67 ...

By Anela Šubo, Amela Dervišević, Zulejha Omerbašić, Muhamed Zeid, Selma Spahić, Almir Fajkić, Damir Suljević

Recently, hemoglobin A1c (HbA1c) has been suggested as a predictor of mortality and poor clinical outcome in patients with trauma. The aim of this study was to evaluate the relationship between HbA1c values and clinical outcome in patients with traumatic brain injury (TBI). In a cross-sectional study, a total of 133 TBI patients referred to the eme...

By Sajad Shafiee, Misagh Shafizad, Dorsa Marzban, Samad Karkhah, Mohammad Ghazanfari, Amir Zeydi

Cognitive disorders and chronic diseases such as diabetes are common problems of aging. The aim of this study was to determine and compare the cognitive status of diabetic and non-diabetic elderly in the past ten years in primary health care in Iran. This cross-sectional study was performed on people aged 60 years and older in Kerman, Iran in 2020....

By Vahidreza Borhaninejad, Maryam Saber

This study aimed to predict the molecular targets of cipargamin in humans and estimate the structural dynamics and binding affinity of their interactions compared to that of Plasmodium falciparum P-type ATPase 4 (PfATP4). In silico methods were used in this study which include target prediction, structure modeling and dynamics, and molecular dockin...

By Toluwase Fatoki, Oladoja Awofisayo, Bolanle Faleye

The coronavirus caused the pandemic COVID-19 that has an extensive influence in the world. The virus enters and infects body cells through superficial protein ACE2. Each cell possessing ACE2 is potentially vulnerable to this virus. Since the respiratory system is exposed to the environment and has ACE2, it is one of the first candidates infected by...

By Roshanak Ghobadian, Hossein Khaleghzadeh-Ahangar

Toxoplasmosis modifies various hormones and cytokines in the infected hosts which may result in several disorders. This study was conducted to assess testosterone, DHEA, and prolactin concentration levels among Toxoplasma gondii infected and uninfected infertile couples. Blood samples were collected and sera were separated. The sera were analyzed f...

By Masomeh Bayani, Narges Kalantari, Sedigheh Esmailzadeh, Salman Ghaffari, Soleiman Mahjoub, Faezeh Ghofrani, Taraneh Ghaffari

The objective of this narrative review was to describe the versatile links between mental status and sleep in patients with Parkinson's disease. We searched randomized controlled studies, observational studies, meta-analyses, systematic reviews, and case reports written in English in PubMed during 2015 - 2021. Additionally, to ensure the completene...

By Anastasiia Shkodina, Tymur Iengalychev, Kateryna Tarianyk, Dmytro Boiko, Nataliia Lytvynenko, Andrii Skrypnikov

The paper was aimed at determining the CCL2/MCP-1 level in patients with odontogenic infectious and inflammatory diseases of soft tissues of the maxillofacial area and mediastinum. The study involved 46 patients with odontogenic infectious and inflammatory diseases of soft tissues of the maxillofacial area and 12 healthy volunteers. The level of pa...

By Mariia Faustova, Oleksandr Nazarchuk, Dmytro Dmytriiev, David Avetikov, Galina Loban, Yuliana Babina, Maiia Ananieva

To develop methods for obtaining enlarged perforating flaps on the anterior surfaces of the thoracic and abdominal walls. The study included 16 patients with post-burn breast deformities aged from 5 to 22 years. In the upper part of the anterior surface of the chest, the flaps were formed on the basis of 2, 3 anterior intercostal artery perforator ...

By Feyta Ruslanovych, Zhernov Andriyovych, Zhernov Oleksandrovych, Kozinets Pavlovych

The key links in the etiology and pathogenesis of periodontal tissue diseases are the quantitative and qualitative changes in the composition of the microflora of the oral cavity, with the simultaneous deterioration of oral hygiene, and reduction of local and general immunity, which occurs more often in the presence of somatic diseases. The aim of ...

By Iryna Lisetska, Mikola Rozhko