Aluminium is a metal that disrupts the pro-oxidant and antioxidant balance in tissuess leading to biochemical dyfunction. The present study evaluated the protective effect of rutin on aluminium chloride (AlCl3)-induced hepatorenal toxicity in Wistar rats. Twenty male Wistar rats were divided into four groups: Group 1-control, Group 2 received AlCl3...

By Olu Israel Oyewole, Ayoola Mary Bukoye

Inflammatory bowel disease (IBD) is a significant cause of morbidity and disability in pediatric patients, characterized by chronic intestinal inflammation. Biologic therapies, such as adalimumab and infliximab, are widely used for induction and maintenance of remission. Therapeutic drug monitoring (TDM) enables individualized treatment by optimizi...

By Jasmina Katanić, Dejan Dobrijević, Mirjana Stojšić

Loeffler's endocarditis (LE) is a rare form of inflammatory cardiomyopathy. The condition arises from diffuse eosinophilic infiltration of the endomyocardium, followed by eosinophil degranulation and progressive tissue fibrosis. The aim of this case report is to present a rare form of restrictive cardiomyopathy, LE, in a young female patient, and t...

By Milica Kotur, Nikola Pantić, Lenka Grujičić, Isidora Grozdić-Milojević, Dragana Šobić-Šaranović, Vera Artiko, Strahinja Odalović

Diabetes mellitus is one of the most common chronic diseases in childhood. The aim of this study was to evaluate the oral health of children with type 1 diabetes in relation to the level of glycemic control. 87 children aged 10 to 15 participated in the study, divided into two groups according to the value of glycosylated hemoglobin (HbA1c): 34 chi...

By Mirjana Djuričković, Aleksa Djuričković

Immune checkpoint inhibitors (ICIs) immensely improved outcomes in melanoma patients. Vitiligo-like depigmentation (VLD) is a well-documented adverse event of ICIs which is well tolerated and often associated with prolonged response to treatment. The aim of this study was to assess the effect of VLD occurrence on survival in melanoma patients treat...

By Aleksandar Popović, Ana Stojković, Ana Cvetanović, Andrija Jović, Milica Radić, Irena Conić, Ivan Petković

Immune thrombocytopenic purpura (ITP) is a common cause of thrombocytopenia in pediatric patients, often requiring differentiation from hypoproductive thrombocytopenia. This study assesses the diagnostic accuracy of immature platelet fraction (IPF) parameters in distinguishing ITP from hypoproductive thrombocytopenia. A cross-sectional study was co...

By Shahla Ansari, Zahra Soheilirad

Seat belt syndrome (SBS) is a new pattern of injuries in road traffic accidents (RTAs). It refers to injuries caused by the interaction of the human body and the safety belt and consists of a wide spectrum of injuries (musculoskeletal and visceral). In this paper, we present a case of a front-seat passenger with polytrauma sustained in an RTA, who,...

By Slađana Anđelić, Eleftheria Papadopoulou, Tanja Nikolić, Goran Čolaković, Milena Popović

Quality of sleep (QoS) in the third-trimester of pregnancy has been suggested as a potential risk factor for the onset of non-psychotic postpartum depression (NPPD). The aim of the paper was to investigate whether the quality of sleep in the third-trimester of pregnancy is a risk factor for nonpsychotic postpartum depression (NPPD) in women without...

By Jelena Stojanov, Olivera Žikić, Miodrag Stanković

Wernicke encephalopathy is a rare acute/subacute neurological disorder, commonly caused by prolonged thiamine deficiency in patients who chronically consume alcohol. According to the Caine classification criteria, the clinical diagnosis of this encephalopathy involves at least two of the following four signs: nutritional deficiency, oculomotor dysf...

By Aleksandra Lučić-Prokin, Vladimir Galić, Timea Kokai-Zekić, Vedran Žigić

Naturally-derived anti-inflammatories, such as bilberry (Vaccinium myrtillus), are particularly interesting due to their health benefits. Bilberries are a rich source of primary metabolites such as sugars and organic acids, which give the fruit its taste. They also contain anthocyanins, the most abundant group of secondary metabolites, possessing v...

By Anđela V. Dragićević, Nikola M. Stojanović, Dragana R. Pavlović