Anoctamin 1 (ANO1, TMEM16A) is a transmembrane protein belonging to the ANO family, with a role in the formation of calcium-activated chloride channels (CaCC). It is included in the regulation of physiological processes such as muscle contraction, gastrointestinal motility, secretion, and electrical excitability. Also, recent data suggest that ANO1...

By Vladimir Petrovic, Aleksandra Veličkov, Marko Jović, Julija Radenković, Braca Kundalić, Dušan Miljković, Vukota Radovanović, Goran Radenković

Unhealthy eating habits and a lack of physical activity are well-known risk factors for chronic illnesses, and many countries in transition have struggled to make significant progress in addressing diet-related non-communicable diseases. Education about diet and nutrition is important for public health, and healthcare professionals are essential in...

By Bojana Miladinović, Milica Milutinović, Dušanka Kitić, Milica Randjelović, Nikolina Savić, Katarina Simonović, Maja Nikolić

Although we could not find the registered cases of leptospirosis co-occurring with lymphogranulomatosis, it is important to note that both diseases can affect the immune system. Therefore, the reported case is unique and will be interesting and useful for the physicians of various specialties. We report a case of icterohemorrhagic form of leptospir...

By Borys Fylenko, Ivan Starchenko, Nataliia Roiko, Iryna Kornilova, Anatolii Romanyuk, Mykola Lyndin

Multiple myeloma is the second most common hematological malignancy in which pathological plasma cells secrete monoclonal proteins, ultimately leading to end-organ damage. Albumin, β2-microglobulin, and LDH are considered highly relevant biomarkers for the diagnosis and prognosis of this disease. There are different types of treatment availabl...

By Ina Konstantinović, Irena Ćojbašić, Miodrag Vučić

The present study was performed to evaluate the effect of subanesthetic dosage of ketamine on awakening and anxiety and depression status among patients undergoing coronary bypass graft (CABG) surgery. In this quasi-experimental study, 50 patients scheduled for elective CABG in a tertiary referral hospital were enrolled. Participants were allocated...

By Rasool Ferasatkish, Nahid Aghdaii, Ali Sadeghi, Mohsen Ziyaeifard, Rasoul Azarfarin, Mirahmad Hendinezhad, Anahita Babaei

Perinatal asphyxia (PA) is a condition in which there is a decreased or interrupted blood and oxygen supply to the tissues of the fetus, i.e., the newborn, immediately before, during, or immediately after delivery. It constitutes a significant cause of mortality, accounting for 23-24% of all neonatal deaths. The estimated global incidence of perina...

By Dejan Dobrijević, Biljana Vučković, Jasmina Katanić

Multiple sclerosis (MS) is a chronic, autoimmune demyelinating disease of the central nervous system. The association of vitamin D deficiency, sun exposure, and higher incidence of multiple sclerosis has been known for long, and a number of studies have confirmed anti-inflammatory and neuroprotective properties of vitamin D. Vitamin D receptor (VDR...

By Lazar Bajić, Dejan Savic, Nikola Krstić, Ana Andrejević, Andrija Rančić, Miljana Mladenović, Tatjana Jevtovic Stoimenov

The emergence of the COVID-19 pandemic has underscored the critical importance of accurate and reliable methods for the early detection and management of cases. Traditional approaches to COVID-19 diagnosis often rely on binary classification methods, which may limit their accuracy and robustness. In this study, we propose a novel approach that leve...

By Affaf Khaouane, Latifa Khaouane, Samira Ferhat, Salah Hanini

This meta-analytic study was conducted with the aim of quantitative integrating the findings obtained in individual studies that were concerned with determining the relationship between generalized anxiety disorder (GAD) and emotional dysregulation in studies conducted on non-clinical sample and adult population. The studies included in the meta-an...

By Danica Vukić, Teodora Safiye

Esophagogastric varices develop in 50-60% of patients with liver cirrhosis, and 30% of them have one episode of variceal hemorrhage within two years of variceal diagnosis. The aim of the paper was to present the latest attitudes in the treatment of esophagogastric varices. Literature review. Prevention of first bleeding from esophageal varices (EV)...

By Ivan Grgov, Daniela Benedeto-Stojanov, Biljana Radovanović-Dinić, Milica Grgov, Saša Grgov, Tomislav Tasić