Neutrophil-lymphocyte ratio (NLR) is one of the laboratory biomarkers used in clinical practice to predict severity and mortality of acute pancreatitis (AP), however, there is currently insufficient information about the changes of NLR in the dynamics in relationship with other clinical and laboratory data. To assess the relationship between NLR va...

By Tetiana Formanchuk, Hryhoriy Lapshyn, Mariya Pokidko, Andrii Formanchuk, Igor Vovchuk

Quality of life is a state of complete physical, mental and social well-being. Due to the COVID-19 pandemic, which led to changes in the daily routine, there was a change in the psychosocial functioning of individuals. Given that laryngectomized patients belong to a vulnerable group that requires psychological support after surgery, specific epidem...

By Mirjana Petrović-Lazić, Snežana Babac, Ivana Ilić-Savić

Machine learning (ML) plays a significant role in the fight against the COVID-19 (officially known as SARS-CoV-2) pandemic. ML techniques enable the rapid detection of patterns and trends in large datasets. Therefore, ML provides efficient methods to generate knowledge from structured and unstructured data. This potential is particularly significan...

By Alem Čolaković, Elma Avdagić-Golub, Muhamed Begović, Belma Memić, Adisa Hasković-Džubur

Bullous pemphigoid (BP) is an autoimmune skin disease that typically presents with severe itching and blistering, with or without eczematous and urticarial lesions. Patients with BP are at an increased risk of comorbid conditions, especially neurologic and psychiatric diseases. Several recent studies have found a link between BP and neurological di...

By Arsovska Mirceska, Katerina Damevska, Viktor Simeonovski, Andrija Jović, Danica Tiodorović

Cognitive disorders and chronic diseases such as diabetes are common problems of aging. The aim of this study was to determine and compare the cognitive status of diabetic and non-diabetic elderly in the past ten years in primary health care in Iran. This cross-sectional study was performed on people aged 60 years and older in Kerman, Iran in 2020....

By Vahidreza Borhaninejad, Maryam Saber

This study aimed to predict the molecular targets of cipargamin in humans and estimate the structural dynamics and binding affinity of their interactions compared to that of Plasmodium falciparum P-type ATPase 4 (PfATP4). In silico methods were used in this study which include target prediction, structure modeling and dynamics, and molecular dockin...

By Toluwase Fatoki, Oladoja Awofisayo, Bolanle Faleye

Toxoplasmosis modifies various hormones and cytokines in the infected hosts which may result in several disorders. This study was conducted to assess testosterone, DHEA, and prolactin concentration levels among Toxoplasma gondii infected and uninfected infertile couples. Blood samples were collected and sera were separated. The sera were analyzed f...

By Masomeh Bayani, Narges Kalantari, Sedigheh Esmailzadeh, Salman Ghaffari, Soleiman Mahjoub, Faezeh Ghofrani, Taraneh Ghaffari

The dissolution test is a simple and important in vitro method for assessing the bioequivalence, which aims to compare the bioavailability of generic and branded drugs. It implies the use of a proper apparatus (usually pharmacopoeially defined) in which the dosage form is dissolved, and the dissolution process itself is monitored/quantified using a...

By Ana Marković, Miroslava Spasić, Vesna Savić, Slavica Sunarić, Marija Tasić-Kostov

The aim of the study was to analyze and compare consultation lengths in Emergency Medical Service (EMS) Belgrade ambulatory clinic which relates to patient age, gender, existing diagnoses and prescribed treatment (therapy or referral to another healthcare institution). We analyzed the data from the electronic database on consultation lengths from o...

By Slavoljub Živanović, Miloranka Petrov-Kiurski

Caring for COVID-19 patients at home is a global challenge. This study aimed to review recommendations put forward on home care for patients with suspected COVID-19 presenting with mild clinical features. This is a review of the scientific literature covering COVID-19 and home care from the medical electronic databases such as PubMed, ProQuest, Goo...

By Javad Dehghannezhad, Vahid Zamanzadeh, Damanabad Heydarpoor, Hadi Hassankhani, Malcolm Boyle, Abbas Dadashzadeh