The dissolution test is a simple and important in vitro method for assessing the bioequivalence, which aims to compare the bioavailability of generic and branded drugs. It implies the use of a proper apparatus (usually pharmacopoeially defined) in which the dosage form is dissolved, and the dissolution process itself is monitored/quantified using a...

By Ana Marković, Miroslava Spasić, Vesna Savić, Slavica Sunarić, Marija Tasić-Kostov

Infective endocarditis (IE) is an important clinical disease in children with a mortality rate of 11.6%. Prophylaxis with antibiotics is one of the most commonly used methods in children at risk of IE; therefore, the evaluation of antibiotic resistance seems necessary in view of its increasing trend. This study aimed to determine the antibiotic sus...

By Morva Moudi, Nilgoon Pasdar, Kazem Babazadeh, Zahra Shahandeh, Farahnaz Sadighian

The aim of the study was to analyze and compare consultation lengths in Emergency Medical Service (EMS) Belgrade ambulatory clinic which relates to patient age, gender, existing diagnoses and prescribed treatment (therapy or referral to another healthcare institution). We analyzed the data from the electronic database on consultation lengths from o...

By Slavoljub Živanović, Miloranka Petrov-Kiurski

In this study, the nutrient contents of "Kati", a fermented cereal-based food, was revealed and antifungal activity of bacteriocin producing lactic acid bacteria (LAB) from "Kati" was assessed against aflatoxigenic Aspergillus flavus (A. flavus). The protein content (9.29%) of "Kati" was higher than (p < 0.05) wet milled-fermented sorghum (6.17%...

By Gabriel Oladimeji, Ogidi Olusola, Olaniyi Oladiti, Bamidele Akinyele

It is of particular importance to use validated questionnaires to remove fear of needles and blood collection, as this public health problem has been observed in a large number of patients and may inadequately affect medical healthcare. The aim of the study was to conduct a research on the reliability of the questionnaire on the fear of blood sampl...

By Suzana Milutinović, Ana Stanković, Sunčica Ivanović, Sanja Trgovčević, Tatjana Kilibarda

The infectious factor is etiological in the caries development. Early colonization of S. mutans is considered as a key point; another important caries-associated microorganism is Lactobacillus, which colonizes carious lesions later. Ecological shifts in the dental plaques against the background of weakened local immunity increase their cariogenicit...

By Loban' Andriivna, Faustova Oleksiivna, Chereda Volodymyrivna, Ananieva Mykolaivna

This is an open uncontrolled study about the positive effects of a four-week rehabilitation spa program on the quality of life of 74 patients with ankylosing spondylitis. We assessed the following health status parameters on admission and discharge from the Institute Igalo, Montenegro: BASFI, BASDAI, ASDAS-CRP, ASAS 20 improvement criteria and SF-3...

By Dušan Mustur

Caring for COVID-19 patients at home is a global challenge. This study aimed to review recommendations put forward on home care for patients with suspected COVID-19 presenting with mild clinical features. This is a review of the scientific literature covering COVID-19 and home care from the medical electronic databases such as PubMed, ProQuest, Goo...

By Javad Dehghannezhad, Vahid Zamanzadeh, Damanabad Heydarpoor, Hadi Hassankhani, Malcolm Boyle, Abbas Dadashzadeh

The apprehensiveness for the knowledge vacuum on existential threat of nasal carriage of pvl+ healthcare-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) strains amongst subjects in hospitals have led us to pursue a grasp on the constellation of staphylococcal cassette chromosome mec (SCCmec) types and pvl gene among mecA positive MRSA...

By Adeiza Suleiman, Onaolapo Ademola, Olayinka Olalekan

Aluminum phosphide, known as "rice tablet" (RT), is a common cause of suicide in adult women in Iran, with a high rate of lethal outcome. We report a patient with RT toxicity, with a complex syndrome of hepatic failure, renal failure, Brugada electrocardiography (ECG) patterns, and pleuropericardial effusion. The patient received conventional manag...

By Feridoun Sabzi, Aghigh Heydari, Reza Moghaddam, Mohammad Rouzbahani, Atefeh Asadmobini