Effectiveness of Tocilizumab after switching from intravenous to subcutaneous formulation in patients with rheumatoid arthritis: A single-centre experience
Nowadays, the appropriate control of rheumatoid arthritis (RA) involves the absence of clinical disease activity, delaying joint destruction as long as possible and adequate quality of life of the affected. With currently available therapeutic modalities, this therapeutic goal can be achieved in a large number of patients. The aim of this research ...
By Sonja Stojanović, Bojana Stamenković, Jovan Nedović, Ivana Aleksić, Jovana Cvetković
Positive effects of a four-week rehabilitation spa program on quality of life in patients with ankylosing spondylitis
This is an open uncontrolled study about the positive effects of a four-week rehabilitation spa program on the quality of life of 74 patients with ankylosing spondylitis. We assessed the following health status parameters on admission and discharge from the Institute Igalo, Montenegro: BASFI, BASDAI, ASDAS-CRP, ASAS 20 improvement criteria and SF-3...
By Dušan Mustur
Shocked to happy: Experiences of Iranian diabetics in reaction to the bad news of the diagnosis
Diagnosis of a chronic disease like type 2 diabetes mellitus (T2DM) is frequently shocking for patients, which influences their lives. Getting aware of bad news such as obtaining a chronic illness diagnosis is a sensitive issue in patients' lives. Conversely, reactions to the reception of a diagnosis of diabetes are often varied for a few reasons. ...
By Areshtanab Namdar, Moonaghi Karimi, Maryam Vahidi, Leila Jouybari, Zeydi Emami, Hossein Ranjbar
Possible health benefits of polyphenols in neurological disorders associated with COVID-19
Novel Coronavirus disease 2019 (COVID-19) represents an emergent global health burden that has challenged the health systems worldwide. Since its sudden upsurge in 2019, many COVID-19 patients have exhibited neurological symptoms and complications. Till now, there is no known effective established drug against the highly contagious COVID-19 infecti...
By Oladele Olaleye, Oladele Titilope, Oyeleke Moses
The burden of tuberculosis as a permanent medical and legal challenge for mankind through centuries
Tuberculosis (TB) is a contagious disease, and throughout human history, it has been permanently opening numerous medical and legal questions, for which the answers are implied by the current social circumstances. In ancient times, insufficient knowledge of the etiopathogenesis of TB resulted in discrimination and isolation of patients. In the Midd...
By Milan Radović, Aleksandar Đorđević, Borislav Božanić
Ultrastructural analysis of the surface changes on the nickel-titanium endodontic instruments after multiple use
One of the primary goals in endodontics is efficient cleaning and shaping of the root canal while maintaining its original configuration. Numerous studies highlight the advantage of using nickel-titanium instruments and the most important is their high flexibility and the ability to penetrate the curved canals. The aim of this study was to analyze ...
By Nenad Stošić, Jelena Popović, Marija Anđelković-Apostolović, Aleksandar Mitić, Marija Nikolić, Radomir Barac
Ertapenem neurotoxicity in patients with kidney damage: A case report
Ertapenem, a member of the carbapenem group of antibiotics, is a broad-spectrum antibiotic that is effective against multidrug-resistant gram-positive and gram-negative infections. In patients with acute or chronic kidney damage, one of the most serious side effects of ertapenem is neurotoxicity. Various clinical conditions such as seizures, halluc...
By Alper Alp, Yalkin Dalda
In vitro antioxidant properties of 2-imino-benzimidazole and 1,3-thiazolo[3,2-a]benzimidazolone derivatives
Antioxidant properties of 2-[2-imino-5-nitro-3-(2-oxo-2-phenylethyl)-2,3-dihydro-1H-benzimidazol1-yl]-1-phenylethanone (compound 1) and 2-(4-fluorobenzylidene)-6-(phenylcarbonyl)[1,3]thiazolo[3,2a]benzimidazol-3(2H)-one (compound 2) were evaluated in vitro. Compounds 1 and 2 did not show significant radical scavenging activity. It has been suggeste...
By Katarina Tomović, Jelena Mrmošanin, Denitsa Yancheva, Anelia Mavrova, Andrija Šmelcerović
Comparison of the effects of heparin 1000 and 5000 units on arterial blood gases
Analysis of arterial blood gases is necessary for managing the respiratory and metabolic parameters of patients in the intensive care unit. The aim of this study was to compare the effects of heparin 1000 and heparin 5000 units on arterial blood gases in patients admitted to the intensive care unit. This study was a triple-blinded clinical trial. A...
By Reza Borabadi, Mostafa Rad, Mohammad Rakhshani, Mojtaba Rad
Chronic partial rupture of the Achilles tendon: The Flexor Hallucis Longus (FHL) tendon transfer: A report of two cases
Achilles tendon injuries most commonly occur in athletes, but also in the middle-aged population practicing recreational sports. The aetiology of injury and disease of the Achilles tendon has not been completely clarified. While acute injury can be attributed to trauma, research showed that a chronic degenerative process is present in most ruptures...
By Mihajlo Mitrović, Dražen Jelača, Ivana Mitrović