Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, with chronic inflammation recognized as a critical factor in its pathogenesis. This review focuses on the roles of pro-inflammatory cytokines interleukin-6 (IL-6) and interleukin-17A (IL-17A), alongside the anti-inflammatory cytokine interleukin-10 (IL-10), in CR...

By Lana Sarajlić, Edin Hodžić, Alma Mekić Abazović, Samir Muhović, Amina Mehić, Emsad Halilović, Salem Bajramagić, Adnan Kulo, Ramajana Šukić-Karalić

Anoctamin-1 (ANO1, TMEM16A), a transmembrane protein belonging to the ANO family, plays a role in the formation of calcium-activated chloride channels (CaCCs). It is involved in the regulation of physiological processes, including muscle contraction, gastrointestinal motility, secretion, and electrical excitability. Also, recent data suggest that A...

By Vladimir Petrovic, Aleksandra Veličkov, Marko Jović, Julija Radenković, Braca Kundalić, Dušan Miljković, Vukota Radovanović, Goran Radenković

Effective doctor-patient communication is central to medical practice, and medical history forms a large part of it. Medical history taking as the most frequently performed task by physicians is, therefore, referred to as the most effective and adaptable tool in clinical practice. Adequate communication and interpersonal skills include active liste...

By Nataša Šelmić

Honey, propolis, and royal jelly are natural products of bees that have been used for medicinal purposes for centuries. The aim of this study is to investigate a comparative study on the therapeutic effect of honey, propolis, and royal jelly collected from two regions of Algeria. The study evaluated the antibacterial activity of hive product using ...

By Mabrouka Bouacha, Ines Boudiar

Loeffler's endocarditis (LE) is a rare form of inflammatory cardiomyopathy. The condition arises from diffuse eosinophilic infiltration of the endomyocardium, followed by eosinophil degranulation and progressive tissue fibrosis. The aim of this case report is to present a rare form of restrictive cardiomyopathy, LE, in a young female patient, and t...

By Milica Kotur, Nikola Pantić, Lenka Grujičić, Isidora Grozdić-Milojević, Dragana Šobić-Šaranović, Vera Artiko, Strahinja Odalović

Diabetes mellitus is one of the most common chronic diseases in childhood. The aim of this study was to evaluate the oral health of children with type 1 diabetes in relation to the level of glycemic control. 87 children aged 10 to 15 participated in the study, divided into two groups according to the value of glycosylated hemoglobin (HbA1c): 34 chi...

By Mirjana Djuričković, Aleksa Djuričković

Aluminium is a metal that disrupts the pro-oxidant and antioxidant balance in tissues, leading to biochemical dysfunction. The present study evaluated the protective effect of rutin on aluminium chloride (AlCl3)-induced hepatorenal toxicity in Wistar rats. Twenty male Wistar rats were divided into four groups: Group 1-control, Group 2 received AlCl...

By Olu Israel Oyewole, Ayoola Mary Bukoye

COVID-19 infection may exacerbate glycemia and lead to metabolic problems in people with diabetes. Emerging data suggest that diabetes may also develop during coronavirus infection in individuals with no prior history of the disease. This study aimed to analyze the prevalence of new-onset hyperglycemia and diabetes mellitus (nDM) in COVID-19 patien...

By Samar Maher Yassin, Zaid Al-Attar

Venomous snakebites in Serbia are neither too frequent nor extremely dangerous. Nevertheless, some can lead to complications or even death. On December 24, 2023, a young man was admitted to hospital after being bitten by a snake, believed to be Vipera ammodytes. He was in a state of shock, unconscious, with unmeasurable blood pressure. Having recei...

By Slađana Pavić, Sonja Nikolić

Many markers are used to evaluate the prognosis in patients with acute myocardial infarction (AMI). Researches are focused on available markers with high sensitivity and specificity. The aim of our study was to evaluate the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and its superiority compared with other prognostic ma...

By Rada Vučić, Vladimir Ignjatović, Olivera Andrejić, Katarina Čupić, Miodrag Srećković, Filipović Vučković, Marija Sekulić, Milan Dobrić, Jelena Rakočević