Inflammatory bowel disease (IBD) is a significant cause of morbidity and disability in pediatric patients, characterized by chronic intestinal inflammation. Biologic therapies, such as adalimumab and infliximab, are widely used for induction and maintenance of remission. Therapeutic drug monitoring (TDM) enables individualized treatment by optimizi...

By Jasmina Katanić, Dejan Dobrijević, Mirjana Stojšić

Approximately 50% of embryo transfer cycles are performed as frozen embryo transfer (FET) cycles; however, research on the factors influencing pregnancy rates in these cycles is limited in northern Iran. The aim of this study was to identify the factors influencing the clinical pregnancy rate in hormone replacement therapy (HRT) FET cycles among in...

By Sepideh Peivandi, Samaneh Aghajanpour, Mohammad Khademloo, Keshvar Samadaee Gelehkolaee, Marzieh Zamaniyan

Multiple sclerosis (MS) is a chronic, autoimmune demyelinating disease of the central nervous system. The association of vitamin D deficiency, sun exposure, and higher incidence of multiple sclerosis has been known for long, and a number of studies have confirmed anti-inflammatory and neuroprotective properties of vitamin D. Vitamin D receptor (VDR...

By Lazar Bajić, Dejan Savic, Nikola Krstić, Ana Andrejević, Andrija Rančić, Miljana Mladenović, Tatjana Jevtovic Stoimenov

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in pediatric population and adolescents. Limited data is available on the characteristics of RMS in Iraqi pediatric patients. The aim of the study was to examine the clinical and histological aspects of RMS in Iraqi children, with a focus on their response to treatment, prognosis, and su...

By Abbas Olewi, Manaf Ahmed, Salih Mahdi, Zaid Al-Attar

Drug-induced esophageal injuries are rare in clinical practice. Doxycycline is the most common antibiotic that can damage the esophagus. We present a 26-year-old woman who visited a gastroenterologist because of difficulty swallowing and pain during swallowing. After laparoscopic treatment of endometriosis, the gynecologist prescribed her doxycycli...

By Stojanov Benedeto, Gordana Petrović, Andrija Rančić, Jovičić Milentijević, Radmila Veličković, Nebojša Ignjatović, Dragan Stojanov

Pre-eclampsia is a major cause of perinatal mortality. Glutamate plays a critical function in the promotion of a healthy pregnancy. Therefore, the aim of this study was to determine the extent of the correlation between pre-eclampsia and 4-hydroxyglutamate acid. This is a case-control study that was conducted on a sample of 100 pregnant women in th...

By Noor Fawzi, Sheikh Al

Patients classified as belonging to simplified pulmonary embolism severity index (sPESI) class 0 are considered to have low-risk pulmonary embolism (PE). Yet, certain laboratory and echocardiographic parameters not accounted for in the sPESI score might suggest a likelihood of worse outcomes in PE cases. This study seeks to determine if the prognos...

By Aleksandra Kozić, Sonja Šalinger, Zorica Dimitrijević, Dragana Stanojević, Tomislav Kostić, Boris Džudović, Irena Mitevska, Jovan Matijašević, Aleksandar Nešković, Vladimir Miloradović, Tamara Kovačević-Preradović, Ana Kovačević-Kuzmanović, Slobodan Obradović

Oral mucositis is an acute, inflammatory, and ulcerative condition of the oral mucosa caused by chemotherapy and/or radiotherapy. Considering the frequency of oral mucositis, its impact on the physical and mental health of patients, as well as the depletion of the economic capacities of an individual and society, the importance of prevention and ma...

By Bojan Poposki, Kiro Ivanovski, Ana Pejčić, Vlatko Kokolanski, Ivana Stanković

Artificial intelligence (AI) is increasingly recognized as a novel tool in enhancing psychotherapy, particularly for adolescents. The integration of AI-based platforms into mental health care promises improved accessibility, personalized interventions, and support for therapeutic processes. We aimed to evaluate the usability, safety, and preliminar...

By Miodrag Stanković, Aleksandra Stojanović

Behçet’s disease is a systemic, chronic, idiopathic inflammatory illness of unknown etiology with a recurrent course, manifested by a characteristic triad: recurrent aphthous stomatitis, ulcerative changes in the mucous membranes and skin of the genital organs, and inflammatory changes in the eyes. In addition, the musculoskeletal syst...

By Vita Ruzhanska, Iuliia Pashkova, Dmytro Grebeniuk, Andrii Sidorov, Svitozar Prevar, Oleksandr Smiiukha, Yuriy Hnatiyk, Arina Ivanitsa