Inflammatory bowel disease (IBD) is a significant cause of morbidity and disability in pediatric patients, characterized by chronic intestinal inflammation. Biologic therapies, such as adalimumab and infliximab, are widely used for induction and maintenance of remission. Therapeutic drug monitoring (TDM) enables individualized treatment by optimizi...

By Jasmina Katanić, Dejan Dobrijević, Mirjana Stojšić

Nizon-Isidor syndrome (NIZIDS) is a rare genetic disorder associated with mutations in the MED12L gene and is usually characterized by a distinctive facial appearance, neurodevelopmental delay, autism spectrum disorders (ASD), and chronic gastrointestinal symptoms (GIS). In this case report, we emphasize the importance of early evaluation of geneti...

By Mehmet Semih Demirtaş, Yakup Köylü

Older edentulous adults often rely on mucosa-supported complete dentures (CDs) due to limitations that preclude implant therapy. Although an adequate retention of maxillary CD is essential for functional efficiency, compression of the palatal mucosa during impression making may compromise palatal mucosal microcirculation during denture wear. T...

By Petar Tekić, Stefan Vulović, Marija Milić, Marko Igić, Milena Kostić, Aleksandra Popovac, Ivica Stančić, Aleksandra Milić Lemić

Loeffler's endocarditis (LE) is a rare form of inflammatory cardiomyopathy. The condition arises from diffuse eosinophilic infiltration of the endomyocardium, followed by eosinophil degranulation and progressive tissue fibrosis. The aim of this case report is to present a rare form of restrictive cardiomyopathy, LE, in a young female patient, and t...

By Milica Kotur, Nikola Pantić, Lenka Grujičić, Isidora Grozdić-Milojević, Dragana Šobić-Šaranović, Vera Artiko, Strahinja Odalović

Diabetes mellitus is one of the most common chronic diseases in childhood. The aim of this study was to evaluate the oral health of children with type 1 diabetes in relation to the level of glycemic control. 87 children aged 10 to 15 participated in the study, divided into two groups according to the value of glycosylated hemoglobin (HbA1c): 34 chi...

By Mirjana Djuričković, Aleksa Djuričković

When making complete dentures, both functional and aesthetic criteria need to be met so that the patient can accept the prosthetic restoration more easily and be satisfied with it. The aim of the research was to determine smile parameters as anthropological criteria for the selection of teeth when making complete dentures. The study included 91 den...

By Milena Kostić, Marko Igic, Marija Đorđević, Ermin Đerlek, Ana Pejcic, Nikola Gligorijević, Ivana Stankovic, Nadica S. Đorđević, Marija Andjelkovic Apostolovic

Retinitis pigmentosa (RP) is a diverse group of inherited retinal diseases characterized by the gradual degeneration of rod and cone photoreceptors in the retina. RP is primarily inherited, with numerous genetic mutations implicated in its pathogenesis. The aim of this study was to summarize the findings of studies related to genes implicated in re...

By Olivia Narváez, Zerón Mendieta, Orlando Torres, Magally Escobar, Martha Trujillo-Güiza

Breast cancer (BC) represents a globally significant health issue, with incidence rates varying worldwide. Radiotherapy is crucial in treating BC, however, it can cause adverse effects, including skin reactions. The aim of this research was to evaluate the impact of two different radiotherapy fractionation regimens on the occurrence and severity of...

By Milica Radić, Andrija Jović, Ana Cvetanović, Ivan Petković, Dane Krtinić, Katarina Krasić, Sandra Radenković, Slavica Stojnev, Irena Conić

Although we could not find the registered cases of leptospirosis co-occurring with lymphogranulomatosis, it is important to note that both diseases can affect the immune system. Therefore, the reported case is unique and will be interesting and useful for the physicians of various specialties. We report a case of icterohemorrhagic form of leptospir...

By Borys Fylenko, Ivan Starchenko, Nataliia Roiko, Iryna Kornilova, Anatolii Romanyuk, Mykola Lyndin

Multiple myeloma is the second most common hematological malignancy in which pathological plasma cells secrete monoclonal proteins, ultimately leading to end-organ damage. Albumin, β2-microglobulin, and LDH are considered highly relevant biomarkers for the diagnosis and prognosis of this disease. There are different types of treatment availabl...

By Ina Konstantinović, Irena Ćojbašić, Miodrag Vučić