Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, with chronic inflammation recognized as a critical factor in its pathogenesis. This review focuses on the roles of pro-inflammatory cytokines interleukin-6 (IL-6) and interleukin-17A (IL-17A), alongside the anti-inflammatory cytokine interleukin-10 (IL-10), in CR...

By Lana Sarajlić, Edin Hodžić, Alma Mekić Abazović, Samir Muhović, Amina Mehić, Emsad Halilović, Salem Bajramagić, Adnan Kulo, Ramajana Šukić-Karalić

Anoctamin-1 (ANO1, TMEM16A), a transmembrane protein belonging to the ANO family, plays a role in the formation of calcium-activated chloride channels (CaCCs). It is involved in the regulation of physiological processes, including muscle contraction, gastrointestinal motility, secretion, and electrical excitability. Also, recent data suggest that A...

By Vladimir Petrovic, Aleksandra Veličkov, Marko Jović, Julija Radenković, Braca Kundalić, Dušan Miljković, Vukota Radovanović, Goran Radenković

Effective doctor-patient communication is central to medical practice, and medical history forms a large part of it. Medical history taking as the most frequently performed task by physicians is, therefore, referred to as the most effective and adaptable tool in clinical practice. Adequate communication and interpersonal skills include active liste...

By Nataša Šelmić

Aluminium is a metal that disrupts the pro-oxidant and antioxidant balance in tissues, leading to biochemical dysfunction. The present study evaluated the protective effect of rutin on aluminium chloride (AlCl3)-induced hepatorenal toxicity in Wistar rats. Twenty male Wistar rats were divided into four groups: Group 1-control, Group 2 received AlCl...

By Olu Israel Oyewole, Ayoola Mary Bukoye

COVID-19 infection may exacerbate glycemia and lead to metabolic problems in people with diabetes. Emerging data suggest that diabetes may also develop during coronavirus infection in individuals with no prior history of the disease. This study aimed to analyze the prevalence of new-onset hyperglycemia and diabetes mellitus (nDM) in COVID-19 patien...

By Samar Maher Yassin, Zaid Al-Attar

This erratum is published to address inaccuracies in the first affiliation of the author of the above-mentioned article. The first affiliation, as presented on the title page, the last page, and within the abstract in Serbian, was not cited consistently. In addition, the official name of the clinic changed shortly after the article’s publicat...

By Acta Facultatis Medicae Naissensis Editorial Board

Rheumatoid arthritis (RA) is a systemic autoimmune disease that can cause destructive joint disease and progressive disability. The diagnosis of RA is based on laboratory and clinical evidence, which includes the analysis of inflammatory markers, hematological, and biochemical parameters. Fifty patients diagnosed with RA without methotrexate (MTX) ...

By Maja Mitrašinović-Brulić, Ema Maslo, Muhamed Fočak, Damir Suljević

Ketorolac is a potent non-steroidal anti-inflammatory drug (NSAID) that can inhibit cyclooxygenase activity and prostaglandin synthesis, thereby reducing pain and inflammation. The aim of this study was to investigate the hepatorenal toxicity of ketorolac administration in adult male rats. Twenty-four adult male Wistar rats were randomly assigned t...

By Fatemeh Rashidi, Amir Noyani, Salma Omidi, Touraj Assadi

Many markers are used to evaluate the prognosis in patients with acute myocardial infarction (AMI). Researches are focused on available markers with high sensitivity and specificity. The aim of our study was to evaluate the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and its superiority compared with other prognostic ma...

By Rada Vučić, Vladimir Ignjatović, Olivera Andrejić, Katarina Čupić, Miodrag Srećković, Filipović Vučković, Marija Sekulić, Milan Dobrić, Jelena Rakočević

Isolated  fallopian tube torsion is a rare condition, especially in adolescents, and can often be misdiagnosed due to nonspecific symptoms. We report the case of a 13-year-old sexually inactive girl who was admitted to Shahid Mobini Hospital in Sabzevar, Iran, with worsening pain in the right lower abdomen and hypogastrium over the past four d...

By Behnaz Souizi, Mehrnaz Mehrdoost, Marzie Torkmannejad Sabzevari, Narjes Forouhar