Malocclusions are common oral health issues that require precise assessment of severity and the need for orthodontic treatment. The Index of Orthodontic Treatment Need (IOTN) is a reliable tool for objectively evaluating the necessity of orthodontic therapy. This study aimed to determine the need for orthodontic treatment among children and adolesc...

By Andjelka Cvijić, Iva Jakovljević, Aleksandra Arnaut, Roberta Marković, Tatjana Čutović

Inflammatory bowel disease (IBD) is a significant cause of morbidity and disability in pediatric patients, characterized by chronic intestinal inflammation. Biologic therapies, such as adalimumab and infliximab, are widely used for induction and maintenance of remission. Therapeutic drug monitoring (TDM) enables individualized treatment by optimizi...

By Jasmina Katanić, Dejan Dobrijević, Mirjana Stojšić

Nizon-Isidor syndrome (NIZIDS) is a rare genetic disorder associated with mutations in the MED12L gene and is usually characterized by a distinctive facial appearance, neurodevelopmental delay, autism spectrum disorders (ASD), and chronic gastrointestinal symptoms (GIS). In this case report, we emphasize the importance of early evaluation of geneti...

By Mehmet Semih Demirtaş, Yakup Köylü

Older edentulous adults often rely on mucosa-supported complete dentures (CDs) due to limitations that preclude implant therapy. Although an adequate retention of maxillary CD is essential for functional efficiency, compression of the palatal mucosa during impression making may compromise palatal mucosal microcirculation during denture wear. T...

By Petar Tekić, Stefan Vulović, Marija Milić, Marko Igić, Milena Kostić, Aleksandra Popovac, Ivica Stančić, Aleksandra Milić Lemić

SGLT-2 inhibitors have been associated with increases in hemoglobin and hematocrit levels; however, the independence of this effect from confounding factors remains unclear in real-world settings. This study aimed to determine whether hemoglobin and hematocrit levels differed between patients with type 2 diabetes mellitus using SGLT-2 inhibitors an...

By Ali Turunç, Melike Saday Bozkurt

The transition process to adulthood is a challenging but crucial period for the future well-being of patients with chronic diseases. The objective of this study was to evaluate whether specific clinical variables and disease activity status are associated with improved transition readiness among patients with juvenile idiopathic arthritis (JIA) and...

By Dragana Lazarević, Hristina Stamenković, Stefan Đorđević, Dušica Novaković, Maja Zečević, Gordana Sušić

Preterm prelabor rupture of membranes (PPROM) is a major cause of neonatal morbidity and mortality. Placental Protein 14 (PP14), a glycodelin glycoprotein, has emerged as a potential biomarker for the diagnosis of PPROM. The study aimed to evaluate the diagnostic accuracy of PP14 in detecting fetal membrane rupture. This case-control study was cond...

By Alaa Ali Rahi, Miami Abdul Hassan Ali

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects the reproductive, metabolic, and psychological health of women of reproductive age. Conventional therapies for PCOS primarily focus on symptom management; however, their associated side effects have led many women to explore complementary approaches. This review aimed to ...

By Gala Žarković, Vladimir Jakovljević, Saša Raičević, Angela Ćorić, Rosa Čukić Ćorović, Nikola Jović, Jovana Joksimović Jović

Artificial intelligence (AI) represents a global phenomenon changing all spheres of human life. Biomedical engineering is no exception, as many AI systems are applied to biomedical engineering inventions. The European Union has enacted the new EU AI Act, one of the world’s first laws on AI. The main topic of this research is to examine what c...

By Srdjan Djordjević, Nikola Ivković, NIkola Milosavljević

Pre-eclampsia is a major cause of perinatal mortality. Glutamate plays a critical function in the promotion of a healthy pregnancy. Therefore, the aim of this study was to determine the extent of the correlation between pre-eclampsia and 4-hydroxyglutamate acid. This is a case-control study that was conducted on a sample of 100 pregnant women in th...

By Noor Fawzi, Sheikh Al