Anoctamin-1 (ANO1, TMEM16A), a transmembrane protein belonging to the ANO family, plays a role in the formation of calcium-activated chloride channels (CaCCs). It is involved in the regulation of physiological processes, including muscle contraction, gastrointestinal motility, secretion, and electrical excitability. Also, recent data suggest that A...

By Vladimir Petrovic, Aleksandra Veličkov, Marko Jović, Julija Radenković, Braca Kundalić, Dušan Miljković, Vukota Radovanović, Goran Radenković

Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, with chronic inflammation recognized as a critical factor in its pathogenesis. This review focuses on the roles of pro-inflammatory cytokines interleukin-6 (IL-6) and interleukin-17A (IL-17A), alongside the anti-inflammatory cytokine interleukin-10 (IL-10), in CR...

By Lana Sarajlić, Edin Hodžić, Alma Mekić Abazović, Samir Muhović, Amina Mehić, Emsad Halilović, Salem Bajramagić, Adnan Kulo, Ramajana Šukić-Karalić

Effective doctor-patient communication is central to medical practice, and medical history forms a large part of it. Medical history taking as the most frequently performed task by physicians is, therefore, referred to as the most effective and adaptable tool in clinical practice. Adequate communication and interpersonal skills include active liste...

By Nataša Šelmić

Honey, propolis, and royal jelly are natural products of bees that have been used for medicinal purposes for centuries. The aim of this study is to investigate a comparative study on the therapeutic effect of honey, propolis, and royal jelly collected from two regions of Algeria. The study evaluated the antibacterial activity of hive product using ...

By Mabrouka Bouacha, Ines Boudiar

Parkinson's disease (PD) is a chronic, neurodegenerative disorder that in certain stages can present a series of acute symptoms and signs, the development of which lasts several hours or days. Emergencies in PD can be a direct consequence of the pathophysiology of the disease or a secondary consequence of the administration of antiparkinsonian drug...

By Jelena Stamenović, Vuk Milošević, Vanja Đurić

Venomous snakebites in Serbia are neither too frequent nor extremely dangerous. Nevertheless, some can lead to complications or even death. On December 24, 2023, a young man was admitted to hospital after being bitten by a snake, believed to be Vipera ammodytes. He was in a state of shock, unconscious, with unmeasurable blood pressure. Having recei...

By Slađana Pavić, Sonja Nikolić

Arteriovenous fistula (AVF) is recommended as the ideal vascular access for hemodialysis (HD), however, there are conflicting opinions when it comes to patients with diabetes mellitus (DM). The aim of the paper was to determine the predictive parameters of AVF maturation for HD in patients with DM. The investigation was organized as a retrospective...

By Radojica Stolić, Marija Milić, Vekoslav Mitrović, Bratislav Lazić, Suzana Milutinović, Snezana Lazić, Kristina Bulatović, Vladimir Mitrović, Andrijana Karanović, Sanja Jovanović

Many markers are used to evaluate the prognosis in patients with acute myocardial infarction (AMI). Researches are focused on available markers with high sensitivity and specificity. The aim of our study was to evaluate the prognostic value of N-terminal pro brain natriuretic peptide (NT-proBNP) and its superiority compared with other prognostic ma...

By Rada Vučić, Vladimir Ignjatović, Olivera Andrejić, Katarina Čupić, Miodrag Srećković, Filipović Vučković, Marija Sekulić, Milan Dobrić, Jelena Rakočević

Glioblastomas (GBMs) are among the most vascularized human tumors and the presence of microvascular proliferation is one of the diagnostic hallmarks of these malignancies. The aim of the present study was to investigate the extent of vascularization and its relation to proliferative activity and the p53 status in GBMs. Tissue samples from 100 selec...

By Desanka Tasić, Irena Dimov, Miloš Kostov, Dragan Dimov

In childhood, infections of the central nervous system may lead to neurodevelopmental disorders and complications such as epilepsy. The present study aimed to evaluate epilepsy in children with central nervous system (CNS) infections. The present systematic review and meta-analysis included five cohort studies from international databases, PubMed, ...

By Mahsa Afrand, Niusha Rostampur, Zeinab Pourhadi, Javad Rezanezhad, Pouriya Nekoueifard